{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:03:08Z","timestamp":1789380188714,"version":"build-2803163510"},"reference-count":52,"publisher":"Wiley","issue":"38","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFA1506700"],"award-info":[{"award-number":["2023YFA1506700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2026,9,14]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Sulfonimidamides are highly appealing owing to their capacity for extensive structural diversification and their broad\u2010spectrum, versatile bioactivities. In the present work, functionalized chiral sulfonimidamides bearing both 1,3\u2010\n                    <jats:italic>S<\/jats:italic>\n                    (VI)\u2010 and\n                    <jats:italic>C<\/jats:italic>\n                    \u2010stereocenters were successfully synthesized via the desymmetrization of sulfonimidamides, which was realized by the highly diastereo\u2010 and enantioselective conjugate addition of 3\u2010bromo\u20103\u2010substituted oxindoles to sulfonimidamides, with a chiral\n                    <jats:italic>N,N<\/jats:italic>\n                    \u2032\u2010dioxide\/Ni(II) complex serving as the Lewis acid catalyst. This transformation features mild reaction conditions, excellent functional group tolerance, and a broad substrate scope.\n                  <\/jats:p>","DOI":"10.1002\/anie.8164022","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:22:28Z","timestamp":1784118148000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Simultaneous Construction of Sulfur and Carbon Stereocenters via Asymmetric Desymmetrization of Sulfonimidamides With Oxindole Derivatives"],"prefix":"10.1002","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4093-7758","authenticated-orcid":false,"given":"Shiya","family":"Li","sequence":"first","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0745-9549","authenticated-orcid":false,"given":"Maoping","family":"Pu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5168-3823","authenticated-orcid":false,"given":"Zhishan","family":"Su","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuihua","family":"Chu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Tan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqiao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jixian","family":"Tao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8723-6793","authenticated-orcid":false,"given":"Lili","family":"Lin","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4507-0478","authenticated-orcid":false,"given":"Xiaoming","family":"Feng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry &amp; Technology College of Chemistry Ministry of Education Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf102765x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41061\u2010017\u20100169\u20109"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41061\u2010018\u20100184\u20105"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2018.11.017"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201302209"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960\u2010894X(99)00241\u20103"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201610456"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201402497"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201200014"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm960673l"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacsau.2c00626"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.5c01027"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c00374"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c06674"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202407114"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5c03973"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202109160"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5SC01270H"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202506929"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010025\u201065132\u20100"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41557\u2010023\u201001419\u20103"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202521905"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202500170"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202510595"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.4c04798"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c13758"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5c04553"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5c00316"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5c02496"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4QO01749H"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01665"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.04.088"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm701383e"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm0496234"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar200015s"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.7b00377"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.1c00664"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.31635\/ccschem.023.202303417"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.5c00370"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c17425"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c01228"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c15392"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202505725"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5SC01054C"},{"key":"e_1_2_8_46_1","unstructured":"CCDC2528152forC10contains the supplentary crystallographic data for this paper. These data are provided free of charge by the joint Cambridge Crystallographic Data Centre and Fachinformationszentrum Karlsruhe Access Structures service."},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00692"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3QO01151H"},{"key":"e_1_2_8_49_1","first-page":"799","article-title":"Asymmetric Catalytic Alkylation of Vinyl Azides With 3\u2010Bromo Oxindoles: Water\u2010Assisted Chemo\u2010and Enantiocontrol","volume":"66","author":"Zhong Z. W.","year":"2023","journal-title":"Science China Chemistry"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4CC00802B"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.31635\/ccschem.020.202000443"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.3c06130"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4CC03327B"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.8164022","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.8164022","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.8164022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T09:08:45Z","timestamp":1789376925000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.8164022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,15]]},"references-count":52,"journal-issue":{"issue":"38","published-print":{"date-parts":[[2026,9,14]]}},"alternative-id":["10.1002\/anie.8164022"],"URL":"https:\/\/doi.org\/10.1002\/anie.8164022","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,15]]},"assertion":[{"value":"2026-02-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8164022"}}