{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T10:50:05Z","timestamp":1791888605900,"version":"4.3.4"},"reference-count":83,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFA1510301"],"award-info":[{"award-number":["2024YFA1510301"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22571031"],"award-info":[{"award-number":["22571031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["DUT22LAB606"],"award-info":[{"award-number":["DUT22LAB606"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2026,5,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Biological photosynthesis harnesses multiple visible light photons to drive thermodynamically demanding reactions, whereas realizing analogous multi\u2010photon excitation in artificial photosynthesis remains challenging. Inspired by enzymatic cascades, we herein report a host\u2013guest supramolecular approach to boosting consecutive multi\u2010photon excitation (&gt;2 photons) by confining a 9\u2010mesityl\u201010\u2010methylacridinium perchlorate (\n                    <jats:bold>\n                      Acr\n                      <jats:sup>+<\/jats:sup>\n                    <\/jats:bold>\n                    ) guest within a coordination supramolecular host assembled from triphenylamine\u2010derived ligands (\n                    <jats:bold>TPA<\/jats:bold>\n                    ) with Ce\u2500O\n                    <jats:italic>t<\/jats:italic>\n                    \u2010Bu nodes for efficient inert C(\n                    <jats:italic>sp<\/jats:italic>\n                    <jats:sup>3<\/jats:sup>\n                    )\u2500H bond activation and transformation. The composition and structure of the consecutive multi\u2010photon excitation host\u2013guest supramolecular system were characterized by a combination of high\u2010resolution electrospray ionization mass spectrometry, NMR, UV\u2013vis spectrum, fluorescence spectrum, and isothermal titration calorimetry. The multi\u2010photon excitation host\u2013guest supramolecular system furnished a catalytic proficiency of 50 h\n                    <jats:sup>\u22121<\/jats:sup>\n                    for the oxidative arylation of inert C(\n                    <jats:italic>sp<\/jats:italic>\n                    <jats:sup>3<\/jats:sup>\n                    )\u2500H bond, representing an approximately 88\u2010fold increase compared to methods employing strong oxidants or harsh acids, and obviously superior to the best previously reported more than two\u2010photon system based on consecutive excitation at a single site. To our knowledge, this represents the first example of consecutive multi\u2010photon excitation integrating three separated photo\u2010responsive sites within a host\u2013guest supramolecular system, which reaches superactivity for inert C(\n                    <jats:italic>sp<\/jats:italic>\n                    <jats:sup>3<\/jats:sup>\n                    )\u2500H bond transformation, offering an attractive avenue toward low\u2010energy light\u2010driven challenging chemical transformations under mild conditions.\n                  <\/jats:p>","DOI":"10.1002\/anie.8289757","type":"journal-article","created":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T07:51:54Z","timestamp":1774684314000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Host\u2013Guest Supramolecular Approach to Boosting Consecutive Multi\u2010Photon Excitation for the Arylation of Inert C(\n                    <i>sp<\/i>\n                    <sup>3<\/sup>\n                    )\u2500H Bonds"],"prefix":"10.1002","volume":"65","author":[{"given":"Yu","family":"Zhang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Fine Chemicals Frontier Science Center For Smart Materials School of Chemical Engineering Dalian University of Technology  Dalian P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8197-6686","authenticated-orcid":false,"given":"Liang","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Fine Chemicals Frontier Science Center For Smart Materials School of Chemical Engineering Dalian University of Technology  Dalian P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwei","family":"Wei","sequence":"additional","affiliation":[{"name":"Hebei Technology Innovation Center for Energy Conversion Materials and Devices, College of Chemistry and Materials Science Hebei Normal University  Shijiazhuang P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"He","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Fine Chemicals Frontier Science Center For Smart Materials School of Chemical Engineering Dalian University of Technology  Dalian P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huali","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Fine Chemicals Frontier Science Center For Smart Materials School of Chemical Engineering Dalian University of Technology  Dalian P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1638-6633","authenticated-orcid":false,"given":"Chunying","family":"Duan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Coordination Chemistry Nanjing University  Nanjing P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41578\u2010020\u20100222\u20100"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay2058"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00286"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201049006\u20105"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1258232"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c09837"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adw1648"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c02832"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201905485"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202307759"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202416472"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202404293"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201053115\u20106"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202001231"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201915762"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.2c00759"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.3c00102"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41557\u2010023\u201001415\u20107"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010025\u201055893\u2010z"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41929\u2010020\u201000528\u20103"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c17218"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201608229"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00763"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202209879"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.8b00261"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c07355"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c05899"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.8b00463"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202319488"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmaterialslett.3c00491"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/446391a"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00263"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00075D"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.4c00510"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202425668"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.6b00057"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7CC08200B"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b07178"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2021.214355"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202008259"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.2c01030"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202114490"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c10664"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4CS00222A"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c09282"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c11981"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.8b00336"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2021.06.003"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c10725"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201913303"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44160\u2010024\u201000697\u20100"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202507981"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrc.1962"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c13756"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1039\/C0CS00062K"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201704327"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b08693"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c10126"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd8408"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b13051"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201052788\u20103"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c10008"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202408358"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9TA03001H"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201209584"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b12043"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202206108"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad3087"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201016714\u20107"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1248859"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotochemrev.2019.100338"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja8013055"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b08781"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202300597"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c05994"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.2c02997"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c02912"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202310697"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.9b04916"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201306510"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b13211"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44160\u2010025\u201000799\u20103"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b12918"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.8289757","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.8289757","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.8289757","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T10:23:17Z","timestamp":1791886997000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.8289757"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,28]]},"references-count":83,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2026,5,4]]}},"alternative-id":["10.1002\/anie.8289757"],"URL":"https:\/\/doi.org\/10.1002\/anie.8289757","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,28]]},"assertion":[{"value":"2026-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e8289757"}}