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We report a Ni(0)\u2010catalyzed enantioselective redox\u2010neutral three\u2010component coupling of aldehydes, sulfonamides, and terminal alkenes that provides formal imino\u2013ene\u2010type products. Enabled by in situ sulfonyl imine generation and a chiral SIPHOS\u2010PE phosphoramidite ligand, the reaction furnishes\n                    <jats:italic>N<\/jats:italic>\n                    \u2010sulfonyl homoallylic amines with high regioselectivity and excellent enantioselectivity. The method is most effective for aliphatic aldehydes and allylarene\u2010derived terminal alkenes, while functionalized allyl esters, allyl phosphonates, heteroaryl alkenes, and complex\u2010molecule\u2010derived substrates are also tolerated. Mechanistic experiments and DFT calculations are consistent with a nickelacycle\u2010mediated pathway involving imine\/alkene oxidative cyclization. This work establishes a redox\u2010neutral asymmetric alkene\u2013imine coupling manifold for the three\u2010component synthesis of enantioenriched homoallylic amines from readily available starting materials.\n                  <\/jats:p>","DOI":"10.1002\/anie.8922921","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T06:21:38Z","timestamp":1787811698000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nickel(0)\u2010Catalyzed Enantioselective Three\u2010Component Imino\u2013Ene\u2010Type Coupling of Aldehydes, Sulfonamides, and Alkenes"],"prefix":"10.1002","volume":"65","author":[{"given":"Ye\u2010Wei","family":"Huang","sequence":"first","affiliation":[{"name":"State Key Laboratory and Institute of Elemento\u2010Organic Chemistry College of Chemistry Frontiers Science Center for New Organic Matter Nankai University  Tianjin 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