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However, achieving this control via radical\u2010involved pathways remains a formidable frontier due to the transient nature of open\u2010shell intermediates. Here, we report a unified chromium\u2010catalyzed platform that harnesses a radical\u2013polar crossover mechanism to achieve the fully ligand\u2010controlled stereodivergent synthesis of chiral\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2010fluoro alcohols. We demonstrate that the stereochemical outcome is not inherent to the substrate but is dictated by the ancillary ligand through distinct non\u2010covalent interactions: a chiral bisoxazoline ligand enforces a rigid transition state via fluorine\u2010mediated hydrogen bonding to selectively deliver\n                    <jats:italic>syn<\/jats:italic>\n                    \u2010diastereomers, whereas a chemically distinct pyridine\u2013imidazoline ligand exploits electronic desymmetrization via \u03c0\u2013\u03c0 stacking to invert selectivity toward\n                    <jats:italic>anti<\/jats:italic>\n                    \u2010isomers. Notably, this protocol enables the programmable assembly of all four stereoisomers of fluorosugar derivatives.\n                  <\/jats:p>","DOI":"10.1002\/anie.9365925","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T13:03:57Z","timestamp":1785935037000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chromium\u2010Catalyzed Stereodivergent Carbonyl Addition Dictated by Non\u2010Covalent Interactions"],"prefix":"10.1002","volume":"65","author":[{"given":"Tianbing","family":"Yao","sequence":"first","affiliation":[{"name":"Zhejiang Key Laboratory of Precise Synthesis of Functional Molecules Department of Chemistry School of Science and Research Center For Industries of the Future Westlake University  Hangzhou Zhejiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyang","family":"Bi","sequence":"additional","affiliation":[{"name":"Zhejiang 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