{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T07:53:17Z","timestamp":1782460397908,"version":"3.54.5"},"reference-count":39,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:00:00Z","timestamp":1772582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:00:00Z","timestamp":1772582400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22322307"],"award-info":[{"award-number":["22322307"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92461313"],"award-info":[{"award-number":["92461313"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22473110"],"award-info":[{"award-number":["22473110"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011179","name":"Institute of Chemistry, Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["CCNC\u2010202501"],"award-info":[{"award-number":["CCNC\u2010202501"]}],"id":[{"id":"10.13039\/501100011179","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2026,4,13]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Catalytic direct oxidation of methane with molecular oxygen can be highly exothermic in thermodynamics. It offers a promising green method for production of value\u2010added chemicals such as formaldehyde (CH\n                    <jats:sub>2<\/jats:sub>\n                    O), an indispensable feedstock in industry, under mild conditions. However, it faces a long\u2010standing grand challenge due to the intrinsic kinetic inertness of methane. Herein, an active gold\u2010tungsten oxide cluster catalyst, AuWO\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>+<\/jats:sup>\n                    , being able to spontaneously catalyze CH\n                    <jats:sub>4<\/jats:sub>\n                    + O\n                    <jats:sub>2<\/jats:sub>\n                    \u00a0\u2192\u00a0CH\n                    <jats:sub>2<\/jats:sub>\n                    O + H\n                    <jats:sub>2<\/jats:sub>\n                    O at room temperature has been successfully identified by mass spectrometry, which is distinctly different from the related condensed phase catalysis wherein the photo\u2010excitation of catalysts in the presence of H\n                    <jats:sub>2<\/jats:sub>\n                    O or H\n                    <jats:sub>2<\/jats:sub>\n                    was prerequisite to initiate catalytic reactions. The previously unrecognized mechanisms of direct methane oxidation have been unveiled: the interfacial Au\u2212metal centers can undergo thermal reaction with O\n                    <jats:sub>2<\/jats:sub>\n                    to spontaneously generate the active (O\u00b7\u00b7\u00b7O)\n                    <jats:sup>\u2212\u2022<\/jats:sup>\n                    hole that subsequently works together with Au atom in a relay\u2010manner to easily cleave two C\u2212H bonds of methane directional for CH\n                    <jats:sub>2<\/jats:sub>\n                    O and H\n                    <jats:sub>2<\/jats:sub>\n                    O production. This finding lays a solid foundation for future design of better\u2010performing catalysts for direct oxidation of methane (or other molecules) with O\n                    <jats:sub>2<\/jats:sub>\n                    without the need of any external energy or co\u2010feeding with alien molecules.\n                  <\/jats:p>","DOI":"10.1002\/anie.9570287","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:36:33Z","timestamp":1772994993000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Direct Oxidation of Methane to Formaldehyde With Molecular Oxygen Catalyzed by Gold\u2010Tungsten Oxide Cluster Cations"],"prefix":"10.1002","volume":"65","author":[{"given":"Yu\u2010Ting","family":"Xiao","sequence":"first","affiliation":[{"name":"State Key Laboratory For Structural Chemistry of Unstable and Stable Species Institute of Chemistry Chinese Academy of Sciences  Beijing China"},{"name":"University of Chinese Academy of Sciences  Beijing China"},{"name":"Beijing National Laboratory for Molecular Sciences and Center for Carbon Neutral Chemistry Institute of Chemistry Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4425-5211","authenticated-orcid":false,"given":"Yan\u2010Xia","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory For Structural Chemistry of Unstable and Stable Species Institute of Chemistry Chinese Academy of Sciences  Beijing China"},{"name":"University of Chinese Academy of Sciences  Beijing China"},{"name":"Beijing National Laboratory for Molecular Sciences and Center for Carbon Neutral Chemistry Institute of Chemistry Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng\u2010Gui","family":"He","sequence":"additional","affiliation":[{"name":"State Key Laboratory For Structural Chemistry of Unstable and Stable Species Institute of Chemistry Chinese Academy of Sciences  Beijing China"},{"name":"University of Chinese Academy of Sciences  Beijing China"},{"name":"Beijing National Laboratory for Molecular Sciences and Center for Carbon Neutral Chemistry Institute of Chemistry Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1515\/revce\u20102014\u20100022"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/biology13080572"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.9b03128"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.7b02388"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0920\u20105861(96)00256\u20108"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201038334\u20107"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/aenm.202406119"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41893\u2010024\u201001401\u2010y"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202206841"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.5c00883"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.202201238"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010025\u201059465\u2010z"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcata.2006.01.043"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.1c08739"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c13313"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cattod.2025.115354"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202202297"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b10139"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.8b00403"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.organomet.6b00372"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201108363"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/cplu.202400085"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/cphc.202400513"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpclett.2c03786"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201200015"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp971941"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201601965"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1039\/b100538n"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201704892"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201805908"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201406497"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6SC00539J"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201403953"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b03940"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199411741"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp200160r"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcatb.2020.119661"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja412608b"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar990028j"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.9570287","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.9570287","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.9570287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T07:28:41Z","timestamp":1776238121000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.9570287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,4]]},"references-count":39,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2026,4,13]]}},"alternative-id":["10.1002\/anie.9570287"],"URL":"https:\/\/doi.org\/10.1002\/anie.9570287","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,4]]},"assertion":[{"value":"2025-12-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9570287"}}