{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:45:04Z","timestamp":1792039504135,"version":"4.4.0"},"reference-count":36,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U24A2083"],"award-info":[{"award-number":["U24A2083"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Solar\u2010driven H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    photosynthesis offers a sustainable route to on\u2010site oxidant production, yet the selective reduction of triplet O\n                    <jats:sub>2<\/jats:sub>\n                    to spin\u2010paired H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    remains kinetically challenging. Covalent organic framework (COF) photocatalysts have largely focused on charge separation and active\u2010site reactivity, while overlooking the spin character of electrons transferred to O\n                    <jats:sub>2<\/jats:sub>\n                    . Here we discover that chiralization renders COFs significantly enhanced production of H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    , and report a chiralization strategy for spin\u2010regulated H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    photosynthesis in \u03b2\u2010ketoenamine\u2010linked COFs. The chiral frameworks enable spin\u2010selective electron transport, favor the O\u2013O\u2010bond\u2010preserving reduction pathway and lower the apparent kinetic barrier for H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    formation. Chiralization enhances H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    production by 38.7%\u2013252.1% relative to achiral counterparts. A bipyridine\u2010containing chiral COF reaches 22.8\u00a0mmol g\n                    <jats:sup>\u22121<\/jats:sup>\n                    h\n                    <jats:sup>\u22121<\/jats:sup>\n                    using solely water and oxygen, with an apparent quantum yield of 10.3% at 420\u00a0nm, placing it at the forefront of sacrificial\u2010agent\u2010free COF systems. Membrane\u2010integrated chiral COFs enable continuous\u2010flow H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    production. These findings establish chirality as a design parameter coupling spin\u2010selective electron transport with O\n                    <jats:sub>2<\/jats:sub>\n                    reduction pathway control, opening new directions for COF photocatalysis.\n                  <\/jats:p>","DOI":"10.1002\/anie.9797011","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:54:05Z","timestamp":1792036445000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chiralizing Covalent Organic Frameworks to Boost H\n                    <sub>2<\/sub>\n                    O\n                    <sub>2<\/sub>\n                    Photosynthesis"],"prefix":"10.1002","author":[{"given":"Shijia","family":"Luo","sequence":"first","affiliation":[{"name":"Key Lab of Functional Polymers for Sustainability of Jiangsu School of Energy and Environment Southeast University  Nanjing Jiangsu P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinglin","family":"Gao","sequence":"additional","affiliation":[{"name":"Key Lab of Functional Polymers for Sustainability of Jiangsu School of Energy and Environment Southeast University  Nanjing Jiangsu P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1533-8018","authenticated-orcid":false,"given":"Congcong","family":"Yin","sequence":"additional","affiliation":[{"name":"Key Lab of Functional Polymers for Sustainability of Jiangsu School of Energy and Environment Southeast University  Nanjing Jiangsu P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8653-514X","authenticated-orcid":false,"given":"Yong","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Lab of Functional Polymers for Sustainability of Jiangsu School of Energy and Environment Southeast University  Nanjing Jiangsu P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201040007\u20104"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoen.2022.107906"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/aenm.202301047"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2202650119"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202315146"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2413609122"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.3c00661"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/d5ee04313a"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.5c07855"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43586\u2010022\u201000181\u2010z"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00550"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44160\u2010024\u201000542\u20104"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201040991\u20107"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41929\u2010023\u201001102\u20103"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44160\u2010025\u201000880\u2010x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5c22772"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44160\u2010026\u201001077\u20106"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/nsr\/nwae332"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201040367\u2010x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c13032"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202412380"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5c14333"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201031096\u20108"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010018\u201003689\u20109"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c00285"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c01097"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1039\/d4nr01232a"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202216310"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c13394"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp509974z"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpclett.0c00474"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c08966"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201504725"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmmm.2023.171157"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00161"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.6c00229"}],"container-title":["Angewandte 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