{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:34:52Z","timestamp":1756996492258},"reference-count":9,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2005,12,9]],"date-time":"2005-12-09T00:00:00Z","timestamp":1134086400000},"content-version":"vor","delay-in-days":5882,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1989,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Twelve members of the Indiana hereditary amyloidosis type II kindred were tested for the presence of amyloid deposits. All were young adults (age 26\u201337), with no evidence of disease and with 1 affected parent. Six were found to be carriers of the variant gene, by DNA testing and\/or reduced serum retinol\u2010binding protein levels. Nevertheless, no amyloid could be found in any skin, rectal, or carpal tunnel biopsy specimens. Our results suggest that hereditary amyloidosis type II is a true late\u2010onset disease, in which accumulation of amyloid does not start until late in life\u2014perhaps only a short time before symptoms appear.<\/jats:p>","DOI":"10.1002\/anr.1780321119","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T22:40:12Z","timestamp":1171492812000},"page":"1474-1476","source":"Crossref","is-referenced-by-count":13,"title":["Hereditary amyloidosis: Evidence against early amyloid deposition"],"prefix":"10.1002","volume":"32","author":[{"given":"Noam","family":"Harats","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Worth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merrill D.","family":"Benson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,14]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Amyloidosis, Metabolic Basis of Inherited Diseases","author":"Benson MD","year":"1989"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-195609000-00003"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1955.00930020666004"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780261211"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI112675"},{"key":"e_1_2_1_7_2","first-page":"182","article-title":"A DNA test for Indiana\/Swiss hereditary amyloidosis (FAP II)","volume":"43","author":"Wallace MR","year":"1988","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320270216"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.11.1413"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI112573"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fanr.1780321119","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr.1780321119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T11:42:38Z","timestamp":1700739758000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anr.1780321119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,11]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1989,11]]}},"alternative-id":["10.1002\/anr.1780321119"],"URL":"https:\/\/doi.org\/10.1002\/anr.1780321119","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,11]]}}}