{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T19:11:24Z","timestamp":1776625884428,"version":"3.51.2"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"vor","delay-in-days":33,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Reports"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Priming doses of non\u2010depolarising neuromuscular blocking drugs given before administration of anaesthetic agents have been used to hasten the onset of neuromuscular blockade. In the settings of coronavirus disease 2019 (COVID\u201019), this could be used to reduce the apnoeic, and potentially aerosol\u2010generating, window. To our knowledge, we report the first cases of tracheal intubation with rocuronium for COVID\u201019 using the priming principle. Both patients needed their tracheas intubated for severe hypoxia using a rapid sequence induction technique with a priming dose of rocuronium. Despite adequate pre\u2010oxygenation a sudden, unexpected fall in arterial oxygen saturations was observed in both patients after administration of a priming dose of 2\u00a0mg of rocuronium. Clinicians should consider this possible risk associated with priming doses of neuromuscular blocking drugs in the management of patients with respiratory failure due to COVID\u201019.<\/jats:p>","DOI":"10.1002\/anr3.12060","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T09:27:52Z","timestamp":1596446872000},"page":"98-100","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Rocuronium priming for tracheal intubation in COVID\u201019 patients"],"prefix":"10.1002","volume":"8","author":[{"given":"H.","family":"Hoshijima","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology Saitama Medical University Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Nagasaka","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Saitama Medical University Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Saitama Medical University Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Komiyama","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Saitama Medical University Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Mieda","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Saitama Medical University Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Saitama Medical University Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Doi","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Saitama Medical University Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,8,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.18254"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0265021502000844"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2005.00693.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15054"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-020-01591-x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004803"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/56.6.663"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-010-1086-z"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199709000-00032"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199311000-00007"}],"container-title":["Anaesthesia Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12060","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anr3.12060","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T11:22:32Z","timestamp":1759922552000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1002\/anr3.12060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1002\/anr3.12060"],"URL":"https:\/\/doi.org\/10.1002\/anr3.12060","archive":["Portico"],"relation":{},"ISSN":["2637-3726","2637-3726"],"issn-type":[{"value":"2637-3726","type":"print"},{"value":"2637-3726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"2020-06-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}