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Although rare, myoclonus has been associated with intrathecal anaesthetics; however, the exact aetiology remains unclear. In this report, we present a case of delayed spinal myoclonus following the administration of intrathecal bupivacaine to a patient with a known history of restless legs syndrome. The aim of this report is to increase awareness of this rare complication and to contribute to the current body of literature in order that the pathophysiology and potential risk factors may be better understood.<\/jats:p>","DOI":"10.1002\/anr3.12113","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T01:49:03Z","timestamp":1619056143000},"page":"73-75","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Spinal myoclonus following spinal anaesthesia in a patient with restless legs syndrome"],"prefix":"10.1002","volume":"9","author":[{"given":"W.","family":"Sieffien","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Medicine Toronto Western Hospital University Health Network Toronto ON Canada"},{"name":"Department of Anaesthesia and Pain Medicine University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Dinsmore","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Medicine Toronto Western Hospital University Health Network Toronto ON Canada"},{"name":"Department of Anaesthesia and Pain Medicine University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,21]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"93","article-title":"Drug\u2010induced myoclonus","volume":"18","author":"Jimenez\u2010Jimenez FJ","year":"2004","journal-title":"Central Nervous System Drugs"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.4076\/1752-1947-3-7293"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20599"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03022328"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-018-02607-z"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199609000-00067"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0303-8467(88)90013-3"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2015.198"},{"key":"e_1_2_5_10_1","first-page":"573","volume-title":"Miller\u2019s Anesthesia","author":"Strichartz GR","year":"2005"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000036606.56405.3D"}],"container-title":["Anaesthesia Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12113","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anr3.12113","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:11:47Z","timestamp":1759936307000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1002\/anr3.12113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/anr3.12113"],"URL":"https:\/\/doi.org\/10.1002\/anr3.12113","archive":["Portico"],"relation":{},"ISSN":["2637-3726","2637-3726"],"issn-type":[{"type":"print","value":"2637-3726"},{"type":"electronic","value":"2637-3726"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2021-03-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}