{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T06:26:24Z","timestamp":1771655184611,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T00:00:00Z","timestamp":1636761600000},"content-version":"vor","delay-in-days":135,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Reports"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Thyroid storm is a rare manifestation of severe thyrotoxicosis, and presentation with coma is highly atypical. A\u00a032\u2010year\u2010old woman, previously euthyroid, presented in a comatose state with tachycardia, hypertension and pyrexia. The patient\u2019s trachea was intubated in the community and she was subsequently admitted to the intensive care unit with a working diagnosis of meningoencephalitis. Although hypertension was present initially, subsequent hypotension necessitated a noradrenaline infusion. The patient remained persistently tachycardic and pyrexial. Initial laboratory investigations, including examination of cerebrospinal fluid, did not identify a specific diagnosis. Subsequently, raised thyroxine and triiodothyronine levels alongside undetectable thyroid\u2010stimulating hormone confirmed the diagnosis of thyroid storm. Following treatment for thyrotoxicosis, the patient made a full recovery and was discharged from the intensive care unit after three days. This case highlights the importance of considering thyroid disease in critically ill patients presenting with non\u2010specific symptoms.<\/jats:p>","DOI":"10.1002\/anr3.12134","type":"journal-article","created":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T10:19:42Z","timestamp":1636798782000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Thyroid storm presenting with coma"],"prefix":"10.1002","volume":"9","author":[{"given":"J. R. L.","family":"McLean","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Allan","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,13]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/2042018810382481"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0334"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/js.2019-00076"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000004078"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2017.0243"},{"key":"e_1_2_5_7_1","first-page":"526","article-title":"Thyroid emergencies","volume":"129","author":"Ylli D","year":"2019","journal-title":"Polish Archives of Internal Medicine"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(18)30165-8"}],"container-title":["Anaesthesia Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12134","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anr3.12134","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12134","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:27:09Z","timestamp":1759944429000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1002\/anr3.12134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1002\/anr3.12134"],"URL":"https:\/\/doi.org\/10.1002\/anr3.12134","archive":["Portico"],"relation":{},"ISSN":["2637-3726","2637-3726"],"issn-type":[{"value":"2637-3726","type":"print"},{"value":"2637-3726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"2021-08-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12134"}}