{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:04:27Z","timestamp":1759971867096,"version":"build-2065373602"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T00:00:00Z","timestamp":1636934400000},"content-version":"vor","delay-in-days":137,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Reports"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:italic>Klebsiella pneumoniae<\/jats:italic> is a common cause of potentially life\u2010threatening infection. This report describes a relapsing healthcare\u2010associated <jats:italic>Klebsiella pneumoniae<\/jats:italic> meningitis in a 60\u2010year\u2010old patient who had SARS\u2010CoV\u20102 infection. During their initial admission for COVID\u201019 pneumonitis and treatment with corticosteroids, the patient developed signs and symptoms suggestive of bacterial meningitis. Blood and cerebrospinal fluid cultures confirmed <jats:italic>Klebsiella pneumoniae<\/jats:italic> as the causative organism. The patient was treated with a prolonged course of high\u2010dose meropenem and made an apparent recovery. Four days after hospital discharge, the patient re\u2010presented critically unwell. <jats:italic>Klebsiella pneumoniae<\/jats:italic> was once again isolated from cerebrospinal fluid. During their second admission, the patient deteriorated despite antimicrobial treatment, and life\u2010sustaining therapies were withdrawn. This case highlights that all COVID\u201019 patients receiving immunosuppressive therapy should be monitored for potential opportunistic infection. Prompt recognition and early antimicrobial therapy are key to improving patient outcomes.<\/jats:p>","DOI":"10.1002\/anr3.12136","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T11:54:30Z","timestamp":1636977270000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Relapsing <i>Klebsiella pneumoniae<\/i> meningitis in a patient with COVID\u201019"],"prefix":"10.1002","volume":"9","author":[{"given":"N.","family":"Ronan","sequence":"first","affiliation":[{"name":"Department of Medical Education Stockport Foundation Trust Stockport UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Jackson","sequence":"additional","affiliation":[{"name":"Departments of Anaesthesia and Intensive Care Stockport Foundation Trust Stockport UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Juhasz","sequence":"additional","affiliation":[{"name":"Departments of Anaesthesia and Intensive Care Stockport Foundation Trust Stockport UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Scarr","sequence":"additional","affiliation":[{"name":"Department of Microbiology Stockport Foundation Trust Stockport UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuy043"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00078-15"},{"key":"e_1_2_5_4_1","first-page":"6634","article-title":"Klebsiella pneumoniae Isolates from Meningitis: epidemiology","volume":"7","author":"Ku Y\u2010H","year":"2017","journal-title":"Virulence and Antibiotic Resistance. 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