{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:03:45Z","timestamp":1759971825976,"version":"build-2065373602"},"reference-count":9,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T00:00:00Z","timestamp":1638489600000},"content-version":"vor","delay-in-days":155,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Reports"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>COVID\u201019 infection immediately after liver transplantation presents a unique and challenging situation. In this report, we present the case of an 11\u2010year\u2010old girl who underwent emergency living donor liver transplantation for acute liver failure. After an uneventful intra\u2010operative course, the patient was transferred to the intensive care unit. On the second postoperative day, the patient developed unexplained severe hypoxia. A polymerase chain reaction test was positive for SARS\u2010CoV\u20102 virus and a hypercoagulable state was indicated by laboratory investigations. Despite therapies such as mechanical ventilation and therapeutic anticoagulation, further clinical deterioration occurred. On the seventh postoperative day, the patient\u2019s pupils were fully dilated bilaterally and unreactive to light, and brain death was later confirmed. This report highlights unique challenges pertaining to oxygenation, coagulation and immunosuppression after liver transplantation in a child with COVID\u201019. Hypoxia of unknown origin in the postoperative period should prompt consideration of COVID\u201019 as a possible cause.<\/jats:p>","DOI":"10.1002\/anr3.12139","type":"journal-article","created":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T19:48:34Z","timestamp":1638560914000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["COVID\u201019 infection in a child following liver transplantation"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4646-5853","authenticated-orcid":false,"given":"G.","family":"Sindwani","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Institute of Liver and Biliary Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7622-1625","authenticated-orcid":false,"given":"S. V.","family":"Abhinaya","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Institute of Liver and Biliary Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1751-5006","authenticated-orcid":false,"given":"M. K.","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Institute of Liver and Biliary Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2597-8625","authenticated-orcid":false,"given":"V.","family":"Pamecha","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Institute of Liver and Biliary Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6275-7736","authenticated-orcid":false,"given":"B. B.","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Paediatric Hepatology Institute of Liver and Biliary Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2002\/328415"},{"key":"e_1_2_5_3_1","first-page":"96","article-title":"COVID\u201019 Lockdown: Impact on liver transplant recipients\u2010 a single centre survey","volume":"68","author":"Jothimani D","year":"2020","journal-title":"Journal of the Association of Physicians of India"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15901"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15909"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.4097\/kja.21006"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2020.10.031"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2015432"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40560-020-00466-z"},{"key":"e_1_2_5_10_1","first-page":"457","article-title":"Liver transplant immunosuppression during the COVID\u201019 pandemic","volume":"43","author":"Forns X","year":"2020","journal-title":"Gastroenterology and Hepatology"}],"container-title":["Anaesthesia Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12139","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anr3.12139","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12139","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:27:10Z","timestamp":1759944430000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1002\/anr3.12139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1002\/anr3.12139"],"URL":"https:\/\/doi.org\/10.1002\/anr3.12139","archive":["Portico"],"relation":{},"ISSN":["2637-3726","2637-3726"],"issn-type":[{"type":"print","value":"2637-3726"},{"type":"electronic","value":"2637-3726"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"2021-11-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12139"}}