{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:30:06Z","timestamp":1786977006590,"version":"build-2736575974"},"reference-count":5,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T00:00:00Z","timestamp":1722988800000},"content-version":"vor","delay-in-days":37,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Reports"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>In this case report, we discuss the use of a thiopentone infusion for the maintenance of anaesthesia in a patient with confirmed malignant hyperthermia susceptibility and carnitine palmitoyltransferase 2 deficiency. The concurrence of both diagnoses precluded the use of both propofol\u2010based total intravenous anaesthesia and volatile inhalational anaesthesia. This patient had been anaesthetised previously with a triple infusion regimen of thiopentone, midazolam and remifentanil and this was a unique opportunity to compare the two instances. Electroencephalogram\u2010based depth of anaesthesia monitoring was in routine use by the time of the second anaesthetic, and thus, the thiopentone infusion could be adjusted accordingly, resulting in a more rapid emergence time. We hope that this case may serve as an example of suitable anaesthetic alternative should both propofol infusion and inhalational anaesthesia not be an option.<\/jats:p>","DOI":"10.1002\/anr3.12318","type":"journal-article","created":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T06:45:18Z","timestamp":1723013118000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Thiopentone\u2010based total intravenous anaesthesia for a patient with carnitine palmitoyltransferase\n                    <scp>II<\/scp>\n                    deficiency and malignant hyperthermia susceptibility"],"prefix":"10.1002","volume":"12","author":[{"given":"Z.","family":"Essackjee","sequence":"first","affiliation":[{"name":"Department of Anaesthesia Salford Royal Hospital  Salford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Sloan","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Salford Royal Hospital  Salford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,7]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"Metabolic Support UK.Carnitine Palmitoyltransferase II Deficiency 2024.https:\/\/metabolicsupportuk.org\/condition\/carnitine\u2010palmitoyltransferase\u2010ii\u2010deficiency\/(accessed 07\/03\/2024)."},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000028853"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2020.09.029"},{"key":"e_1_2_5_5_1","unstructured":"Brighton and Sussex University Hospitals NHS Trust.Thiopental sodium: use in patients with severe traumatic brain injury with refractory raised intracranial pressure in critical care. Department of Critical Care Pharmacy Guideline March 2020.https:\/\/www.bsuh.nhs.uk\/library\/wp\u2010content\/uploads\/sites\/8\/2023\/10\/Thiopental\u2010Raised\u2010ICP\u2010ICU.pdf(accessed 04\/04\/2024)."},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03005465"}],"container-title":["Anaesthesia Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anr3.12318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:10:32Z","timestamp":1759939832000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1002\/anr3.12318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/anr3.12318"],"URL":"https:\/\/doi.org\/10.1002\/anr3.12318","archive":["Portico"],"relation":{},"ISSN":["2637-3726","2637-3726"],"issn-type":[{"value":"2637-3726","type":"print"},{"value":"2637-3726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-07-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12318"}}