{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T13:17:11Z","timestamp":1783516631410,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Continuous wound infusion with local anaesthetics after open abdominal surgery may provide opioid\u2010sparing analgesia, but evidence on very low\u2010concentration regimens is limited. We conducted a prospective observational study including 50 patients receiving continuous infusion of levobupivacaine 0.0625% via pre\u2010peritoneal or subfascial catheters at a flow rate of 12\u2009ml.h\n                    <jats:sup>\u22121<\/jats:sup>\n                    per catheter. Six patients (12%) required intravenous morphine rescue in the first 48\u2009h, with a median dose of 3\u2009mg. Median pain scores remained consistently low and 14 patients (28%) received additional local anaesthetic boluses with effective relief. No major catheter\u2010related complications or systemic local anaesthetic toxicity were observed. Continuous wound infusion with levobupivacaine 0.0625% after open abdominal surgery was feasible and associated with minimal opioid use. These findings provide preliminary evidence supporting the feasibility of an ultralow concentration regimen.\n                  <\/jats:p>","DOI":"10.1002\/anr3.70050","type":"journal-article","created":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T06:47:22Z","timestamp":1769237242000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultralow concentration levobupivacaine 0.0625% for continuous wound infusion after open abdominal surgery: a prospective observational study"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5367-5525","authenticated-orcid":false,"given":"D.","family":"Zamudio","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Critical Care Alcorcon Foundation University Hospital  Madrid 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