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This review systematically examines both traditional and advanced extraction technologies, including membrane filtration, supercritical fluid extraction (SFE), pressurized liquid extraction, chromatographic techniques, micro\u2010 and nano\u2010separation and enzyme\u2010assisted processes, drawing on peer\u2010reviewed English literature from databases like Scopus, Web of Science, ScienceDirect, PubMed and Google Scholar using terms related to eco\u2010friendly extraction, fruit bioactive compounds and technologies such as ultrasound\u2010assisted extraction (UAE), microwave\u2010assisted extraction (MAE), SFE and natural deep eutectic solvents (NADES), supplemented by screening reference lists. Peer\u2010reviewed studies on green extraction methods, solvents, optimization strategies and sustainability were included, whereas non\u2010fruit matrices, insufficiently detailed studies and non\u2010peer\u2010reviewed sources were excluded. Publications from January 2017 to October 2025 were retrieved and considered, with key earlier studies added as needed. The search retrieved about 1203 records; after duplicate removal and independent screening by two reviewers, 456 eligible studies were retained for analysis. Emphasis is placed on eco\u2010friendly methods that maintain compound integrity and enable industrial scalability, alongside discussions of green chemistry, fruit by\u2010product valorization and circular economy strategies. Technologies are assessed for efficiency, selectivity, environmental impact and cost\u2010effectiveness, with applications spanning functional foods, pharmaceuticals, cosmetics and packaging. Despite challenges such as compound stability, regulatory barriers and the need for specialized expertise, emerging hybrid systems and AI\u2010driven process modelling show promise in optimizing extraction and reducing costs. Future research should focus on developing multifunctional green solvents, real\u2010time monitoring tools and closed\u2010loop systems to minimize waste and energy use, ultimately advancing sustainable bioactive extraction and contributing to healthier, more environmentally conscious industries.<\/jats:p>","DOI":"10.1002\/ansa.70071","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T08:10:18Z","timestamp":1772957418000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Advances in Eco\u2010Friendly Extraction of Fruit Bioactive Compounds: Technologies, Challenges and Future Directions"],"prefix":"10.1002","volume":"7","author":[{"given":"Abadi Gebreyesus","family":"Hndeya","sequence":"first","affiliation":[{"name":"Department of Biological and Chemical Engineering Mekelle Institute of Technology Mekelle University  Mekelle Tigray 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