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Sixteen studies that used modern diagnostic criteria and interviewed at least 25 patients on at least two occasions over a minimum follow\u2010up period of one year are reviewed. Results show that, despite the availability of effective anti\u2010panic treatments, panic disorder remains a chronic illness. While most patients improve, few are \u201ccured.\u201d The presence of agoraphobia, major depression and personality disorder seems to predict poorer outcome. The importance of measuring multiple clinical dimensions of panic is emphasized, along with the need to reach a consensus about the definition of \u201coutcome\u201d and the particular instruments to use to measure it. Anxiety 1:151\u2013160 (1994\/1995). \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/anxi.3070010402","type":"journal-article","created":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T11:58:27Z","timestamp":1383825507000},"page":"151-160","source":"Crossref","is-referenced-by-count":63,"title":["Course and outcome in panic disorder: A review of recent follow\u2010up studies"],"prefix":"10.1002","volume":"1","author":[{"given":"Peter P.","family":"Roy\u2010Byrne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah 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