{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:03:40Z","timestamp":1790935420370,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2002,8,12]],"date-time":"2002-08-12T00:00:00Z","timestamp":1029110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[2002,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Saethre\u2010Chotzen syndrome is a common autosomal dominant form of craniosynostosis, the premature fusion of the sutures of the calvarial bones of the skull. Most Saethre\u2010Chotzen syndrome cases are caused by haploinsufficiency for the <jats:italic>TWIST<\/jats:italic> gene. Mice heterozygous for a null mutation of the <jats:italic>Twist<\/jats:italic> gene replicate certain features of Saethre\u2010Chotzen syndrome, but have not been reported to exhibit craniosynostosis. We demonstrate that <jats:italic>Twist<\/jats:italic> heterozygous mice exhibit fusions of the coronal suture and other cranial suture abnormalities, indicating that <jats:italic>Twist<\/jats:italic> heterozygous mice constitute a better animal model for Saethre\u2010Chotzen syndrome than was previously appreciated. Anat Rec 268:90\u201392, 2002. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ar.10124","type":"journal-article","created":{"date-parts":[[2002,10,8]],"date-time":"2002-10-08T22:44:37Z","timestamp":1034117077000},"page":"90-92","source":"Crossref","is-referenced-by-count":75,"title":["Craniosynostosis in <i>Twist<\/i> heterozygous mice: A model for Saethre\u2010Chotzen syndrome"],"prefix":"10.1002","volume":"268","author":[{"given":"Ethan A.","family":"Carver","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen F.","family":"Oram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Gridley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,8,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/7.6.945"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.9.6.686"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0197-42"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63987-9"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0197-36"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/302122"},{"key":"e_1_2_5_8_1","first-page":"507","volume-title":"The atlas of mouse development","author":"Kaufman MH","year":"1992"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1994.1020"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0177(2000)9999:9999<::AID-DVDY1073>3.0.CO;2-F"},{"key":"e_1_2_5_11_1","first-page":"47637","article-title":"Saethre\u2010Chotzen syndrome with familial translocation at chromosome 7p22","author":"Reid CS","year":"1993","journal-title":"Am J Med Genet"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(200002)217:2<137::AID-DVDY1>3.0.CO;2-N"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.8.1369"},{"key":"e_1_2_5_14_1","first-page":"669","article-title":"Evidence for locus heterogeneity in acrocephalosyndactyly: a refined localization for the Saethre\u2010Chotzen syndrome locus on distal chromosome 7p\u2014and exclusion of Jackson\u2010Weiss syndrome from craniosynostosis loci on 7p and 5q","volume":"54","author":"van Herwerden L","year":"1994","journal-title":"Am J Hum Genet"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.10.1647"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.10124","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.10124","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T15:18:12Z","timestamp":1700320692000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ar.10124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8,12]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["10.1002\/ar.10124"],"URL":"https:\/\/doi.org\/10.1002\/ar.10124","archive":["Portico"],"relation":{},"ISSN":["0003-276X","1097-0185"],"issn-type":[{"value":"0003-276X","type":"print"},{"value":"1097-0185","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,8,12]]}}}