{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T19:16:35Z","timestamp":1721070995571},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,10,25]],"date-time":"2002-10-25T00:00:00Z","timestamp":1035504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In order to clarify the role of antioxidant enzymes in the male rat submandibular gland against short\u2010term normobaric oxygenation, we performed immunocytochemical staining of manganese\u2010containing superoxide dismutase (Mn\u2010SOD), copper\u2010 and zinc\u2010containing SOD (Cu\/Zn\u2010SOD), catalase (CAT), glutathione peroxidase, and glutathione <jats:italic>S<\/jats:italic>\u2010transferases (GST alpha, GST mu, and GST pi) between days 1 and 7 after normobaric oxygenation. Ultrastructural alterations and immunoreactivities for malondialdehyde (MDA), a lipid peroxidation\u2010related molecule, of the acinar and ductal cells after the oxygenation were also investigated. Immunoreactivity for MDA was exhibited in the acinar cells throughout the experiment. On the other hand, immunoreactivity for the SODs, CAT, and GSTs was not altered, when compared to that of controls, but was significantly elevated in the granular, striated, and excretory ductal cells. Since an increase of lipid peroxidation as indicated by enhanced immunoreactivity for MDA was detected in the acinar and intercalated ductal cells, the results indicate that the enhanced antioxidant enzymes in the granular, striated, and excretory ductal cells play a crucial role in the self\u2010defense system of the male rat submandibular gland against normobaric oxygenation. Anat Rec 268:371\u2013380, 2002. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ar.10171","type":"journal-article","created":{"date-parts":[[2002,11,6]],"date-time":"2002-11-06T19:00:43Z","timestamp":1036609243000},"page":"371-380","source":"Crossref","is-referenced-by-count":4,"title":["Enhanced immunocytochemical expression of antioxidant enzymes in rat submandibular gland after normobaric oxygenation"],"prefix":"10.1002","volume":"268","author":[{"given":"Miyako","family":"Morita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Kudo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Doi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunio","family":"Ikemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunao","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,11,2]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"359","volume-title":"Pathology of oxygen toxicity","author":"Balentine JD","year":"1982"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1191\/096032700678815594"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910315)67:6<1608::AID-CNCR2820670623>3.0.CO;2-S"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1987.tb02077.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01003001"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(73)80755-0"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000052636"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.2.313"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/21.2.131"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1968.48.2.311"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(92)80198-P"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1016\/S0021-9258(17)35978-1","article-title":"Role of cardiac glutathione transferase and of the glutathione S\u2010conjugate export system in biotransformation of 4\u2010hydroxynonenal in the heart","volume":"261","author":"Ishikawa T","year":"1986","journal-title":"J Biol Chem"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470122914.ch6"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(96)00078-9"},{"key":"e_1_2_6_16_1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2220\/biomedres.11.187","article-title":"Sensitive immunoassay of rat superoxide dismutase: concentration in the brain, liver and kidney are not affected by aging","volume":"11","author":"Kurobe N","year":"1990","journal-title":"Biomed Res"},{"key":"e_1_2_6_17_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2220\/biomedres.12.97","article-title":"Sensitive enzyme immunoassay for rat Mn superoxide dismutase: tissue distribution and developmental profiles in the rat central nervous tissue, liver, and kidney","volume":"12","author":"Kurobe N","year":"1991","journal-title":"Biomed Res"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.17.10630"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.14.8217"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/10409238809088226"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9120(99)00075-2"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-483X(00)00306-1"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(85)80670-0"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2740409"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00158205"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/26.2.179"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.10.3.325"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.2307\/3579045"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02639393"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03339665"},{"key":"e_1_2_6_31_1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.2174\/0929867306666220208213032","article-title":"Glutathione S\u2010transferase\u2014a review","volume":"6","author":"Salinas AE","year":"1999","journal-title":"Curr Med Chem"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/33.8.3894498"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)31568-6"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0940-9602(99)80056-9"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.10171","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.10171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T08:53:32Z","timestamp":1700297612000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ar.10171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11,2]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["10.1002\/ar.10171"],"URL":"https:\/\/doi.org\/10.1002\/ar.10171","archive":["Portico"],"relation":{},"ISSN":["0003-276X","1097-0185"],"issn-type":[{"value":"0003-276X","type":"print"},{"value":"1097-0185","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,11,2]]}}}