{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T09:40:29Z","timestamp":1699782029207},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,1,27]],"date-time":"2005-01-27T00:00:00Z","timestamp":1106784000000},"content-version":"vor","delay-in-days":13236,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[1968,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ultrastructural changes have been induced in liver parenchymal cells of the mouse by postnatal cholecystectomy. The major changes included frequent occurrence of numerous vesicles, frequent development of extensive forms of copious Golgi apparatus and an increase in number of lysosomes and microbodies in the peribiliary cytoplasm, and dilatation of bile canaliculi. The cytoplasm beyond the peribiliary zone, contained numerous large mitochondria which were often associated with abundant granular endoplasmic reticulum. In view of the known cytophysiological roles played by the cytoplasmic components undergoing such changes, an elevated activity of bile secretion is suggested in the liver cells of cholecystectomized animals. The presumed high activity of bile secretion in the cells can be comprehended in terms of a compensatory adaptation to the loss of bile concentrating capability of the biliary system due to the removal of the gallbladder.<\/jats:p>","DOI":"10.1002\/ar.1091620312","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T23:25:13Z","timestamp":1109460313000},"page":"373-385","source":"Crossref","is-referenced-by-count":2,"title":["Ultrastructural changes in liver parenchymal cells of the mouse following postnatal cholecystectomy"],"prefix":"10.1002","volume":"162","author":[{"given":"Kazuyori","family":"Yamada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,1,27]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"187","volume-title":"The transport of bilirubin in the liver. Progress in liver diseases","author":"Arias I. M.","year":"1961"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.12.1.198"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00602983"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1152\/ajplegacy.1958.195.2.301","article-title":"Time relations among metabolic and morphologic 24\u2010hour changes in mouse liver","volume":"195","author":"Barnum C. P.","year":"1958","journal-title":"Am. J. Physiol."},{"key":"e_1_2_1_6_1","first-page":"840","article-title":"Studies on cholestasis. A reevaluation of the fine structure of normal human bile canaliculi","volume":"13","author":"Biava C. G.","year":"1964","journal-title":"Lab. Invest."},{"key":"e_1_2_1_7_1","first-page":"691","article-title":"The fine structure of the parenchymal cells of the normal rat liver. I. General observations","volume":"46","author":"Bruni C.","year":"1965","journal-title":"Am. J. Path."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000141765"},{"key":"e_1_2_1_9_1","first-page":"295","article-title":"The fine structure of mouse liver microbodies","volume":"5","author":"Daems W. T.","year":"1966","journal-title":"J. Microscopie"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1000800303"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00339329"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5320(60)90016-2"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.15.2.289"},{"key":"e_1_2_1_14_1","first-page":"305","article-title":"Lipid transport in liver 1. Electron microscopic identification of very low density lipoproteins in perfused rat liver","volume":"16","author":"Hamilton R. L.","year":"1967","journal-title":"Lab. Invest."},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091200408"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)38900-8"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.11.3.729"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.2.1.33"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.9.2.409"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.16.1.81"},{"key":"e_1_2_1_21_1","first-page":"1637","article-title":"Advantages of a phosphate buffer for osmium tetroxide solutions in fixation","volume":"32","author":"Millonig G.","year":"1961","journal-title":"J. Appl. Physics"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00406295"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.2.4.179"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(60)90011-5"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.15.1.140"},{"key":"e_1_2_1_26_1","first-page":"149","volume-title":"Symposia of the International Society for Cell Biology","author":"Novikoff A. B.","year":"1962"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001200204"},{"key":"e_1_2_1_28_1","first-page":"426","volume-title":"Hndb. mikr. Anat. Mensch.","author":"Pf\u00fchl W.","year":"1932"},{"key":"e_1_2_1_29_1","first-page":"103","volume-title":"Liver: structure and function","author":"Popper H.","year":"1957"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.2.4.355"},{"key":"e_1_2_1_31_1","first-page":"195","volume-title":"The Liver, Morphology, Biochemistry, Physiology","author":"Rouiller C.","year":"1965"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.17.1.19"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.21.2.233"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.34.3.703"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/20.2.99"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.16.2.281"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091510403"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091560108"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.1091620312","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.1091620312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T09:22:58Z","timestamp":1699780978000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ar.1091620312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1968,11]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1968,11]]}},"alternative-id":["10.1002\/ar.1091620312"],"URL":"https:\/\/doi.org\/10.1002\/ar.1091620312","archive":["Portico"],"relation":{},"ISSN":["0003-276X","1097-0185"],"issn-type":[{"value":"0003-276X","type":"print"},{"value":"1097-0185","type":"electronic"}],"subject":[],"published":{"date-parts":[[1968,11]]}}}