{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T17:10:15Z","timestamp":1699809015830},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T00:00:00Z","timestamp":1107302400000},"content-version":"vor","delay-in-days":9955,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[1977,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The morphology of parafollicular (C) cells in the thyroid gland of the woodchuck, <jats:italic>Marmota monax<\/jats:italic>, was studied during the four seasons of the year. The spring C cells are characterized by a large Golgi zone, rough\u2010surfaced endoplasmic reticulum, free ribosomes and relatively few dense granules. In the summer these cells appear to be larger and many are packed with dense granules. Fall cells exhibit morphological characteristics suggestive of intense synthetic activity, having rough\u2010surfaced endoplasmic reticulum in whorls or parallel arrangement, a large Golgi apparatus and few, to many granules, some of which are larger than those seen in the spring and summer C cells. In the winter, most of the C cells are packed with granules. The Golgi zone, when observed, is small and the rough\u2010surfaced endoplasmic reticulum is sparse. Many cell profiles exhibit apparent granule dissolution. These cyclic morphological findings are discussed along with previous studies of other hibernators and are correlated with the seasonal activities of the woodchuck.<\/jats:p>","DOI":"10.1002\/ar.1091890302","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T12:05:05Z","timestamp":1109419505000},"page":"397-411","source":"Crossref","is-referenced-by-count":4,"title":["Seasonal variation in the morphology of thyroid parafollicular (C) cells in the woodchuck, <i>Marmota monax<\/i>: A light and electron microscopic study"],"prefix":"10.1002","volume":"189","author":[{"given":"R.","family":"Frink","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. P.","family":"Krupp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,2]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"5","article-title":"Sulle modificazioni cicliche stagionali e sperimentali dell' epitelio follicolare della tiroide di animali ibernanti. Ateneo Parmense","volume":"38","author":"Azzali G.","year":"1967","journal-title":"Acta Bio\u2010Medica"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-70-5-638"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5320(72)90050-0"},{"key":"e_1_2_1_5_1","first-page":"211","volume-title":"Advances in Pharmacology","author":"Falk B.","year":"1968"},{"key":"e_1_2_1_6_1","first-page":"235","volume-title":"Mammalian Hibernation III","author":"Fisher K. 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Cell Sci."},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1242\/jcs.6.3.821","article-title":"Seasonal changes in secretory grianules and crystalloid inclusions of bat thyroid parafollicular cells","volume":"6","author":"Nunez E. A.","year":"1970","journal-title":"J. Cell Sci."},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00336674"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1966.0044"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00336669"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.2307\/3626942"},{"key":"e_1_2_1_23_1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3109\/10520297109067867","article-title":"The Pearson silver\u2010gelatin method for light microscopy of 0.5\u20102 \u03bc plastic sections","volume":"46","author":"Rosenquist T. H.","year":"1971","journal-title":"Stain Tech."},{"key":"e_1_2_1_24_1","first-page":"337","article-title":"A study on the thyroid gland of bat in winter and early spring. 1. Observations in the light microscope","volume":"20","author":"Velicka J.","year":"1972","journal-title":"Folia Morphologica"},{"key":"e_1_2_1_25_1","first-page":"406","article-title":"A study of the bat thyroid gland in winter and early spring. 2. Electron microscopy observations","volume":"20","author":"Velicky J.","year":"1972","journal-title":"Folia Morphologica"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0110125"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091720109"},{"key":"e_1_2_1_28_1","unstructured":"Young R. A.1975The Woodchuck Marrnota monax as a Biomedical Model for the Study of Obesity. Ph.D. Dissertation University of Vermont May 1975."},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0011-2240(76)90163-2"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.1091890302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.1091890302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T16:40:53Z","timestamp":1699807253000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ar.1091890302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,11]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1977,11]]}},"alternative-id":["10.1002\/ar.1091890302"],"URL":"https:\/\/doi.org\/10.1002\/ar.1091890302","archive":["Portico"],"relation":{},"ISSN":["0003-276X","1097-0185"],"issn-type":[{"value":"0003-276X","type":"print"},{"value":"1097-0185","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,11]]}}}