{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T21:55:22Z","timestamp":1768341322320,"version":"3.49.0"},"reference-count":49,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,1,26]],"date-time":"2005-01-26T00:00:00Z","timestamp":1106697600000},"content-version":"vor","delay-in-days":9249,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[1979,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The ability of the striated ducts of rat salivary glands to incorporate <jats:sup>3<\/jats:sup>H\u2010fucose into glycoprotein was studied by light and electron microscope radioautography. At 3.5 to 20 minutes after intravenous injection, the majority of the radioautographic grains in the ducts of the parotid gland were localized to the Golgi apparatus. By 40 minutes, the percentage of grains over the Golgi apparatus had decreased; a corresponding increase in grains occurred over small (0.1\u20100.4 \u03bcm) apical granules and the highly infolded basal and lateral plasma membranes. By two hours, less than 10% of the label was associated with the Golgi apparatus, while 26% and 28% were attributed to the apical granules and plasma membrane, respectively. By 8 to 12 hours after injection, the number of grains over the apical cytoplasm had decreased, suggesting luminal discharge of the apical granules. In contrast, the basal and lateral plasma membranes remained labeled up to 30 hours after injection as judged by the distribution of grains in light microscope radioautographs. Mitochondria appeared capable of independent incorporation of fucose, accounting for about 20% of the grains from ten minutes to two hours after injection. Comparable results were obtained in the striated ducts of the submandibular and sublingual glands.<\/jats:p><jats:p>These results indicate that the striated duct cells readily incorporate <jats:sup>3<\/jats:sup>H\u2010fucose into newly\u2010synthesized glycoproteins. A portion of these are secretory glycoproteins which are packaged and stored in the apical granules, and a portion are membrane glycoproteins which are incorporated into the extensive plasma membrane of these cells.<\/jats:p>","DOI":"10.1002\/ar.1091950207","type":"journal-article","created":{"date-parts":[[2005,2,27]],"date-time":"2005-02-27T00:14:53Z","timestamp":1109463293000},"page":"317-339","source":"Crossref","is-referenced-by-count":29,"title":["Synthesis of secretory and plasma membrane glycoproteins by striated duct cellsof rat salivary glands as visualized by radioautography after <sup>3<\/sup>H\u2010fucose injection"],"prefix":"10.1002","volume":"195","author":[{"given":"Arthur R.","family":"Hand","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,1,26]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1975.sp011097"},{"key":"e_1_2_1_3_1","first-page":"3873","article-title":"The metabolism of plasma glycoproteins. 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