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Cat carotid and aortic bodies were reacted with antisera to met\u2010 and leu\u2010enkephalin using the indirect peroxidase\u2010antiperoxidase immunocytochemical method of Sternberger (1979). Both the carotid and aortic bodies demonstrated clusters of immunoreactive cells for both met\u2010 and leuenkephalin. Additionally, met\u2010enkephalin\u2010like immunoreactivity was observed in many of the dense\u2010core vesicles of the glomus cells of the carotid body. The glomus cells of these chemoreceptors are known to contain catecholamines which may modulate chemoreceptor activity. The presence of opioid peptide\u2010like substances co\u2010existing with the glomus cell catecholamines, perhaps in the same vesicles, may have important implications for a trophic influence of these peptides on glomus cell chemoreceptor modulation.<\/jats:p>","DOI":"10.1002\/ar.1092030310","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T23:44:06Z","timestamp":1109461446000},"page":"405-410","source":"Crossref","is-referenced-by-count":31,"title":["Localization of enkephalin\u2010like immunoreactivity in the cat carotid and aortic body chemoreceptors"],"prefix":"10.1002","volume":"203","author":[{"given":"John T.","family":"Hansen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Brokaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Christie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Karasek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,1,26]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.42.3.794"},{"key":"e_1_2_1_3_1","first-page":"33","volume-title":"Physiology of Respiration","author":"Comroe J. 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