{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T01:36:21Z","timestamp":1698111381188},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,1,26]],"date-time":"2005-01-26T00:00:00Z","timestamp":1106697600000},"content-version":"vor","delay-in-days":7299,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[1985,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Light microscopic changes were studied in the dorsal funiculi of spinal cords from rats irradiated (4000 R) at 3 days of age and killed from 9\u201360 days postirradiation (P\u2010I). The irradiated site was limited to a 5\u2010mm length of mid\u2010thoracic spinal cord (T only) in one group of rats, to a 5\u2010mm length of lumbosacral spinal cord (L only) in a second group, and to 5\u2010mm lengths of both mid\u2010thoracic and lumbosacral spinal cord (T\/L) in the third group. Changes in the lumbosacral regions were essentially the same in both L only and T\/L irradiated groups. These changes included a decreased neuroglial population and a concurrent state of hypomyelination from 9\u201330 days P\u2010I. In contrast, in the mid\u2010thoracic regions of T only and T\/L irradiated groups the decrease in the neuroglial population was obvious only through 13 days P\u2010I, and by 30 days this population resembled that of the controls. The irradiated mid\u2010thoracic areas were hypomyelinated, with the fasciculus gracilis showing a greater degree of hypomyelination than the fasciculus cuneatus. By 25 days P\u2010I, myelination appeared to be normal in these areas. Scattered hemorrhages were noted in both lumbosacral and mid\u2010thoracic regions, but necrotic areas occurred only at the lumbosacral level. In general, the mid\u2010thoracic area appeared to be less sensitive to x\u2010radiation at 3 days of age than the lumbosacral area. These data suggest that there may be marked differences in the developmental states of cells at these two levels at 3 days of age.<\/jats:p>","DOI":"10.1002\/ar.1092110212","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T23:28:34Z","timestamp":1109460514000},"page":"198-204","source":"Crossref","is-referenced-by-count":12,"title":["A comparison of histopathologic changes following x\u2010irradiation of mid\u2010thoracic and lumbosacral levels of neonatal rat spinal cord"],"prefix":"10.1002","volume":"211","author":[{"given":"Jeanne K.","family":"Heard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirley","family":"Ann Gilmore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,1,26]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"9","article-title":"The induction of demyelination in neonatal kittens by x\u2010irradiation","volume":"196","author":"Anderson W. J.","year":"1980","journal-title":"Anat. Rec."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901630102"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-197401000-00010"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01351538"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(77)90006-5"},{"key":"e_1_2_1_7_1","first-page":"131","article-title":"Roentgen paralysis in the mouse","volume":"71","author":"Brunst V. V.","year":"1954","journal-title":"Am. J. Roentgenol. Rad. Therapy Nuclear Med."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901750205"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-196104000-00008"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-196304000-00008"},{"key":"e_1_2_1_11_1","first-page":"372","article-title":"Early changes in neuroglia following x\u2010irradiation of the neonatal spinal cord","volume":"148","author":"Gilmore S. A.","year":"1964","journal-title":"Anat. Rec."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.16.8.749"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091630111"},{"key":"e_1_2_1_14_1","first-page":"841","volume-title":"Radiation Biology of the Fetal and Juvenile Mammal","author":"Gilmore S. A.","year":"1969"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091710208"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.17.11.1059"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091600403"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092050308"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(82)90515-7"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-196801000-00004"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091970108"},{"key":"e_1_2_1_22_1","first-page":"195","volume-title":"Advances in Teratology","author":"Hicks S. P.","year":"1966"},{"key":"e_1_2_1_23_1","first-page":"35","volume-title":"Studies on the Development of Behavior and the Nervous system","author":"Hicks S. P.","year":"1978"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1979.tb00633.x"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1148\/122.2.505"},{"key":"e_1_2_1_26_1","volume-title":"Late effects of radiation on the spinal cord","author":"Kogel A.","year":"1979"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-47-559-393"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1159\/000144672"},{"key":"e_1_2_1_29_1","first-page":"459","article-title":"New applications of the luxol fast blue myelin stain","volume":"5","author":"Margolis G.","year":"1956","journal-title":"Lab. Invest."},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/99.1.101"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901420102"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(65)90064-6"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901240205"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(82)90001-X"},{"key":"e_1_2_1_35_1","first-page":"236","article-title":"Ultrastructural studies of Schwann cell invasion and myelination in the central nervous system","volume":"199","author":"Sims T. J.","year":"1981","journal-title":"Anat. Rec."},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)90544-9"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-51-607-515"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.1092110212","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.1092110212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T14:08:33Z","timestamp":1697810913000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ar.1092110212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1985,2]]}},"alternative-id":["10.1002\/ar.1092110212"],"URL":"https:\/\/doi.org\/10.1002\/ar.1092110212","archive":["Portico"],"relation":{},"ISSN":["0003-276X","1097-0185"],"issn-type":[{"value":"0003-276X","type":"print"},{"value":"1097-0185","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,2]]}}}