{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:38:45Z","timestamp":1758634725837},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,2,23]],"date-time":"2005-02-23T00:00:00Z","timestamp":1109116800000},"content-version":"vor","delay-in-days":7207,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[1985,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A method for the estimation of the size and total number of calcitonin\u2010containing cells (C cells) in the rat thyroid gland has been devised. The total area, the number of C cells per unit area, and the areal fraction of C cells were determined for the C cell region using step serial sections. From these data it was estimated that from 0.3 \u00d7 10<jats:sup>6<\/jats:sup> to 1.0 \u00d7 10<jats:sup>6<\/jats:sup> C cells were evenly divided between the two thyroid lobes. Approximately 150 \u03bcm<jats:sup>3<\/jats:sup> of cytoplasm were associated with each of these cells. In comparison with sham\u2010operated rats, pinealectomy had little effect on the number of C cells. In an experiment terminated in the summer, there was a statistically insignificant decrease 6 weeks postsurgery; no effect was seen at 12 weeks. On the other hand, a slight increase in the number of C cells was seen in January, 12 weeks postsurgery. The volume of cytoplasm per cell was not altered by pinealectomy.<\/jats:p>","DOI":"10.1002\/ar.1092120210","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T23:31:32Z","timestamp":1109460692000},"page":"167-171","source":"Crossref","is-referenced-by-count":8,"title":["Number and size of rat thyroid C cells: No effect of pinealectomy"],"prefix":"10.1002","volume":"212","author":[{"given":"P. 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