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Rec."],"published-print":{"date-parts":[[1988,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In order to describe initial events in enamel mineralization and to help characterize inorganic\u2010organic interactions in this tissue, the earliest rod and interrod enamel in mandibular incisors from normal young adult (100 gm) rats, perfused with 100% ethylene glycol, has been studied by transmission electron microscopy, selected area electron diffraction, and high\u2010spatial\u2010resolution electron probe microanalysis. Diffraction and probe data were correlated precisely from the same extracellular regions of the tissue. Sites were examined progressively as a function of location (a) from the most recently deposited enamel adjacent to ameloblasts toward the dentin\u2010enamel junction and (b) from the apical portion of the tooth longitudinally toward its incisal end. Electron diffraction patterns consistent with that of a poorly crystalline hydroxyapatite were generated at all locations. Diffraction characteristics changed only slightly toward that of more crystalline hydroxyapatite at different locations. Earliest apical enamel generated molar Ca\/P ratios in a range of 0.99\u20131.46 (average 1.24 \u00b1 0.15). Molar Ca\/P ratios of the first enamel interrod elements increased from \u223c1.24 at ameloblast\u2010enamel boundaries to \u223c1.40 at the dentin\u2010enamel junction, small changes corresponding to those observed in electron diffraction characteristics.<\/jats:p>","DOI":"10.1002\/ar.1092200303","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T22:35:33Z","timestamp":1109457333000},"page":"233-238","source":"Crossref","is-referenced-by-count":23,"title":["Earliest enamel deposits of the rat incisor examined by electron microscopy, electron diffraction, and electron probe microanalysis"],"prefix":"10.1002","volume":"220","author":[{"given":"William J.","family":"Landis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace Y.","family":"Burke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia R.","family":"Neuringer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary C.","family":"Paine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Nanci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hershey","family":"Warshawsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,1,26]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092020202"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00507128"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00496692"},{"key":"e_1_2_1_5_1","first-page":"383","volume-title":"Scanning Electron Microscopy","author":"Casciani F. 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Doctoral Thesis Weizmann Institute of Science Rehovot Israel."},{"key":"e_1_2_1_12_1","first-page":"285","article-title":"Membrane\u2010bound bodies as initiators of mineralization in dentine","volume":"116","author":"Katchburian E.","year":"1973","journal-title":"J. Anat."},{"key":"e_1_2_1_13_1","first-page":"497","volume-title":"Eighth International Congress on X\u2010ray Optics and Microanalysis","author":"Landis W. J.","year":"1980"},{"key":"e_1_2_1_14_1","first-page":"360","volume-title":"The Chemistry and Biology of Mineralized Tissues","author":"Landis W. 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