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The data demonstrate many microstructural similarities between the Pecos and modern populations, even though they were genetically and culturally distinct. Pecos women had small Haversian canals and large osteon mean wall thickness, with no clear evidence of an intracortical bone volume deficit even in the older age groups, although significant marrow cavity expansion occurred in both males and females with age. No striking relationships were found between bone tissue changes and gross geometric changes with age. The data suggest that a more active life\u2010style is associated with greater osteon mean wall thickness or osteon population density, but that it alone does not protect against significant bone loss on the cortical\u2010endosteal surface.<\/jats:p>","DOI":"10.1002\/ar.1092260306","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T21:02:25Z","timestamp":1109451745000},"page":"307-313","source":"Crossref","is-referenced-by-count":98,"title":["Patterns of skeletal histologic change through time: Comparison of an archaic native american population with modern populations"],"prefix":"10.1002","volume":"226","author":[{"given":"David B.","family":"Burr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher B.","family":"Ruff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David D.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,1,26]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"941","article-title":"Metrical studies on the lamellar structure of human long bones","volume":"65","author":"Aoji O.","year":"1959","journal-title":"J. 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