{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T09:07:13Z","timestamp":1774343233427,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,2,8]],"date-time":"2005-02-08T00:00:00Z","timestamp":1107820800000},"content-version":"vor","delay-in-days":5274,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat. Rec."],"published-print":{"date-parts":[[1990,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The morphology and position of the pericyte, a periendothelial cell, is described for a teleost fish, <jats:italic>Cyprinodon variegatus<\/jats:italic>. This cell was found attached to the abluminal surfaces of capillaries, venules, and arterioles of the submucosa of the midgut of the fish. The cell was encompassed by a thin basal lamina, possessed numerous plasmalemmal vesicles, a \u201csole region\u201d which contained thinner actin\u2010like filaments and possibly thicker myosin\u2010like filaments, and ranged in form from ovoid to stellate, with long cytoplasmic extensions that partially covered the endothelium of the associated microvessel. The pericyte of <jats:italic>C. variegatus<\/jats:italic> has been shown to give rise to hemangiopericytomas (experimentally induced with diethylnitrosamine) and possibly to pericytomas. The range of phnotypic expression of these pericyte\u2010derived neoplasms is broad, and dependent upon the degree of differentiation of their constituent cells which range from clear cell pericytes to myofilamentous laden cells that resemble smooth muscle cells. In this regard and in regard to its normal ultrastructural morphology, and anatomical position, in relationship to microvasculature in this fish, the cell is very similar to other vertebrate pericytes. Limited evidence suggests that small fish species may be excellent study models for further elucidation of pericyte form, function, and role in disease.<\/jats:p>","DOI":"10.1002\/ar.1092280103","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T20:47:20Z","timestamp":1109450840000},"page":"7-14","source":"Crossref","is-referenced-by-count":15,"title":["Pericyte of a teleost fish: Ultrastructure, position, and role in neoplasia as revealed by a fish model"],"prefix":"10.1002","volume":"228","author":[{"given":"John A.","family":"Couch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,8]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.37.2.244"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0026-2862(82)90028-0"},{"key":"e_1_2_1_4_1","first-page":"182","article-title":"The phylogeny of the fine structure of blood vessels and lymphatics: similarities and differences","volume":"20","author":"Casley\u2010Smith J. R.","year":"1987","journal-title":"Lymphology"},{"key":"e_1_2_1_5_1","first-page":"297","article-title":"N\u2010nitroso\u2010diethylamine\u2010induced hepatocarcinogenesis in estuarine sheepshead minnow (Cyprinodon variegatus): neoplasms and related lesions compared with mammalian lesions","volume":"79","author":"Couch J. A.","year":"1987","journal-title":"J. Natl. Cancer Inst."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/01913128909057440"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092140113"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/01902148109052325"},{"key":"e_1_2_1_9_1","first-page":"188","article-title":"The effect of continued hypoxia on rat pulmonary arterial circulation","volume":"38","author":"Meyrick B.","year":"1978","journal-title":"Lab. Invest."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0026-2862(84)90019-0"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00234838"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4800(85)90082-6"},{"key":"e_1_2_1_13_1","first-page":"175","article-title":"The pericyte\u2014a review","volume":"18","author":"Sims David E.","year":"1986","journal-title":"Tissue Cell"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.1092280103","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.1092280103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T19:40:40Z","timestamp":1698003640000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ar.1092280103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,9]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1990,9]]}},"alternative-id":["10.1002\/ar.1092280103"],"URL":"https:\/\/doi.org\/10.1002\/ar.1092280103","archive":["Portico"],"relation":{},"ISSN":["0003-276X","1097-0185"],"issn-type":[{"value":"0003-276X","type":"print"},{"value":"1097-0185","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,9]]}}}