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By immunoblot analysis of cytosolic proteins, I\u201015P was detected not only in the distal portion of small intestine but also in the ovary and adrenal gland. Immunohistochemically, I\u201015P was localized to the absorptive epithelial cells as well as a subpopulation of enterochromaffin cells in the intestine, the lutein cells in the ovary, and subpopulations of cortical cells in the adrenal gland. Furthermore, I\u201015P\u2010like immunoreactivity was also demonstrated in the surface mucous cells of stomach and the granular convoluted tubule cells of submandibular gland. Immuno\u2010electron microscopy showed that the immunoreactivity was confined to the cytoplasmic matrix region, except in the enterochromaffin cells and granular convoluted tubule cells, where it was localized in the secretory granules. The present findings suggest that I\u201015P plays a role in the cellular metabolism of steroids.\u00a9 Willey\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ar.1092340208","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T19:56:29Z","timestamp":1109447789000},"page":"215-222","source":"Crossref","is-referenced-by-count":25,"title":["Immunocytochemical localization of rat intestinal 15 kDa protein, a member of cytoplasmic fatty acid\u2010binding proteins"],"prefix":"10.1002","volume":"234","author":[{"given":"Osamu","family":"Amano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruo","family":"Ono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Iseki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,8]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.2.313"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/28.8.7003006"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(86)90314-1"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.17.5468"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00492352"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-123-5-2578"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.12.1.101"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.40.3.692"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"20248","DOI":"10.1016\/S0021-9258(19)47054-3","article-title":"Gastrotropin: Not an exterooxyntin but a member of a family of cytoplasmic hydrophobic ligand binding proteins","volume":"264","author":"Gantz","year":"1989","journal-title":"J. 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