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The primary goal of this study was to determine whether or not IGF\u2010I\u2010like immunoreactivity is present in the oviduct of the vitellogenic American alligator, <jats:italic>Alligator mississippiensis<\/jats:italic>, and if immunoreactivity patterns vary among the three functional oviducal regions: the albumen\u2010secreting tube region, the anterior, fiber\u2010secreting uterus, and the posterior, calcium\u2010secreting uterus. Immunolocalization of IGF\u2010I\u2010like immunoreactivity was accomplished using a polyclonal antihuman rabbit antiserum with an immunoperoxidase staining system. IGF\u2010I\u2010like immunoreactivity was detected in all three oviducal regions of the vitellogenic alligator. The presence of IGF\u2010I\u2010like immunoreactivity in the oviduct suggests this hormone could function in the growth and proliferation of the alligator oviduct. Furthermore, the presence of IGF\u2010I\u2010like immunoreactivity in the tubal glands, which secrete components of the egg white, suggests that growth factors such as IGF\u2010I may be synthesized by these glands and incorporated into the albumen during egg formation. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ar.1092360407","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T19:43:21Z","timestamp":1109447001000},"page":"635-640","source":"Crossref","is-referenced-by-count":15,"title":["Localization of insulin\u2010like growth factor\u2010I\u2010like immunoreactivity in the reproductive tract of the vitellogenic female American alligator, <i>Alligator mississippiensis<\/i>"],"prefix":"10.1002","volume":"236","author":[{"given":"Cathy","family":"Cox","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis J.","family":"Guillette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,1,26]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-6480(89)90143-3"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(90)90154-5"},{"key":"e_1_2_1_4_1","first-page":"85","volume-title":"Modern Concepts of Insulin\u2010like Growth Factors","author":"Bern","year":"1991"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-6480(72)90095-0"},{"key":"e_1_2_1_6_1","first-page":"2005","article-title":"Nucleotide sequence and growth hormone\u2010regulated expression of salmon insulin\u2010like growth factor I mRNA. 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