{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:47:48Z","timestamp":1791344868383,"version":"4.3.1"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2009,5,18]],"date-time":"2009-05-18T00:00:00Z","timestamp":1242604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Anatomical Record"],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Realistic airway geometry is required for accurate biomechanical modeling, particle deposition predictions and ultimately risk assessment and inhaled drug delivery protocols. Morphometric studies to date provide data for specific anatomical locations or for more generational average data for the entire lung. In an attempt to provide a realistic geometry representative of a typical human, the National Institute of Health (NIH) Visible Human (VH)<jats:sup>\u00ae<\/jats:sup> female data set was reconstructed and compared to available morphometric data from the literature. The reconstructed NIH VH female airway model extended from just distal to the larynx down through the fifth generation of bronchial passageways. Casting and scanning techniques were used to create the upper airway geometries so that the model could be used realistically for oral exposure. Each reconstruction stage was examined to show the loss of data during segmentation, decimation, and smoothing processes. The resulting dimensions of the complete female model were consistent with morphometric data from the literature, indicating that the model is a reasonable representation of an adult female that could be used for biomechanical modeling. Anat Rec, 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ar.20898","type":"journal-article","created":{"date-parts":[[2009,5,18]],"date-time":"2009-05-18T14:43:26Z","timestamp":1242657806000},"page":"1028-1044","source":"Crossref","is-referenced-by-count":22,"title":["3D Airway Reconstruction Using Visible Human Data Set and Human Casts with Comparison to Morphometric Data"],"prefix":"10.1002","volume":"292","author":[{"given":"Risa J.","family":"Robinson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jackie","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L.","family":"Doolittle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,5,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001888-199906000-00012"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2003.815905"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.179.2.1790301"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1983.54.5.1269"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/jam.2007.0566"},{"key":"e_1_2_7_7_1","first-page":"476","article-title":"Measurements of airway dimensions and calculation of mass transfer characteristics of the human oral passage","volume":"119","author":"Cheng KH","year":"1997","journal-title":"Trans ASME"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/027868299304165"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/15428110208984697"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(99)90003-4"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","unstructured":"FanL ChenCW.2000.Reconstruction of airway tree based on topology and morphological operations. Medical imaging 2000: physiology and function from multidimensional images.3978:46\u201357.","DOI":"10.1117\/12.383438"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.2201751"},{"key":"e_1_2_7_13_1","volume-title":"Laryngeal biomechanics","author":"Fink B","year":"1978"},{"key":"e_1_2_7_14_1","unstructured":"FloresJM SchmittF.2005. Segmentation reconstruction and visualization of the pulmonary artery and the pulmonary vein from anatomical images of the visible human project. In: Proceedings of the Sixth Mexican International Conference on Computer Science."},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaerosci.2006.01.003"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.146.2.233"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1968.24.3.373"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1971.31.2.207"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2007.02.006"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/02786820802232964"},{"key":"e_1_2_7_21_1","first-page":"356","article-title":"The cross\u2010sectional shape and circumference of the human trachea","volume":"66","author":"Mehta S","year":"1984","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.1.101"},{"issue":"2","key":"e_1_2_7_23_1","first-page":"166","article-title":"Optimalization of MR imaging in some speech disorders causes and a 3D model of the larynx","volume":"13","author":"Peterova L","year":"2006","journal-title":"Eur J Neurol"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092120408"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-005-9049-5"},{"key":"e_1_2_7_26_1","volume-title":"Color atlas of anatomy","author":"Rohen JW","year":"2006"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.1619981"},{"key":"e_1_2_7_28_1","doi-asserted-by":"crossref","unstructured":"SchroederWJ ZargeJA LorensenW.1992. Decimation of triangle meshes. Comput Graph (In: SIGGRAPH Proceedings 1992) p65\u201370.","DOI":"10.1145\/133994.134010"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(03)00179-9"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/jamia.1996.96236280"},{"key":"e_1_2_7_31_1","volume-title":"Gray's anatomy","author":"Standring S","year":"2005"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1089\/jam.2006.19.314"},{"key":"e_1_2_7_33_1","doi-asserted-by":"crossref","unstructured":"ThiesseJ ReinhardtJM de RykJ NamatiE LeinenJ RecheisW HoffmanEA McLennanG.2005.Three\u2010dimensional visual truth of the normal airway tree for use as a quantitative comparison to micro\u2010CT reconstructions. Medical imaging 2005: physiology function and structure from medical images.5746:50\u201357.","DOI":"10.1117\/12.596806"},{"key":"e_1_2_7_34_1","unstructured":"U.S. National Library of Medicine. Available at:nlm.nih.gov. Retrieved February 10 2007."},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-198412000-00007"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.4324\/9780203360637"},{"key":"e_1_2_7_37_1","unstructured":"WeibelER.1964.Morphometrics of the lung. Handbook of physiology section 3: respiration.1:285\u2013307."},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1117\/12.148644"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2005.06.021"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02458596"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1089\/jam.2007.0584"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.20898","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.20898","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:26:04Z","timestamp":1759951564000},"score":1,"resource":{"primary":{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/10.1002\/ar.20898"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,18]]},"references-count":40,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["10.1002\/ar.20898"],"URL":"https:\/\/doi.org\/10.1002\/ar.20898","archive":["Portico"],"relation":{},"ISSN":["1932-8486","1932-8494"],"issn-type":[{"value":"1932-8486","type":"print"},{"value":"1932-8494","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,18]]}}}