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Therefore, I investigated the distribution of ecto\u20105\u2032\u2010nucleotidase (5\u2032\u2010NT), the key enzyme for the production of extracellular adenosine. This report provides evidence that 5\u2032\u2010NT is expressed in the choroid and in the ciliary body (and its processes) of the rat eye, predominantly in endothelial cells. These locations of 5\u2032\u2010NT indicate strategically important production sites of adenosine regulating choroid and ciliary body functions (e.g., blood flow, aqueous fluid production, and immune response). 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