{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T17:55:09Z","timestamp":1776448509565,"version":"3.51.2"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T00:00:00Z","timestamp":1299024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Anatomical Record"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pleuroperitoneal canal (PP canal) closure is generally considered to result from an increase in the height, and subsequent fusion, of the bilateral pleuroperitoneal folds (PP folds). However, the folds develop in the area ventral to the adrenal, in contrast to the final position of the diaphragm, which extends to the dorsal side of the adrenal (the \u201cretro\u2010adrenal\u201d diaphragm). We examined the semiserial histology of 20 human embryos and fetuses (crown\u2010rump length 11\u201340 mm). We started observations of the canal at the stage through which the lung bud extends far caudally along the dorsal body wall to the level of the future adrenal, and the phrenic nerve has already reached the PP fold. Subsequently, the developing adrenal causes narrowing of the dorsocaudal parts of the canal, and provides the bilateral midsagittal recesses or \u201cfalse\u201d bottoms of the pleural cavity. However, at this stage, the PP fold mesenchymal cells are still restricted to the ventral side of the adrenal, especially along the liver and esophagus. Thereafter, in accordance with ascent of the lung, possibly due to anchoring of the liver to the adrenal, the PP fold mesenchymal cells seem to migrate laterally along the coelomic mesothelium covering some sheet\u2010like loose mesenchymal tissue behind the adrenal. Final closure of the PP canal by lateral migration to provide the \u201cretro\u2010adrenal\u201d diaphragm is a process quite different from the common dogma. It is likely that the sheet\u2010like loose mesenchymal tissue becomes the caudal part of the pleural cavity through a process involving cell death. Anat Rec, 2011. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ar.21351","type":"journal-article","created":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T19:15:18Z","timestamp":1299093318000},"page":"633-644","source":"Crossref","is-referenced-by-count":23,"title":["Pleuroperitoneal Canal Closure and the Fetal Adrenal Gland"],"prefix":"10.1002","volume":"294","author":[{"given":"Shogo","family":"Hayashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Fukuzawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Francisco","family":"Rodr\u00edguez\u2010V\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baik Hwan","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Verdugo\u2010L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gen","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,3,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.0010010"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10503"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.PDR.0000057986.74037.7B"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091330208"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2007.01.004"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00027.2008"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20613"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2009-0076OC"},{"key":"e_1_2_5_10_1","first-page":"1092","volume-title":"Gray's Anatomy","author":"Collins P","year":"2005"},{"key":"e_1_2_5_11_1","first-page":"371","volume-title":"Human Embryology","author":"Hamilton WJ","year":"1978"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20995"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20930"},{"key":"e_1_2_5_14_1","first-page":"188","article-title":"Development of the human lesser sac","volume":"91","author":"Kanagasuntheram R","year":"1957","journal-title":"J Anat"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-007-0186-4"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.21351","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.21351","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:11:28Z","timestamp":1759943488000},"score":1,"resource":{"primary":{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/10.1002\/ar.21351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,2]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1002\/ar.21351"],"URL":"https:\/\/doi.org\/10.1002\/ar.21351","archive":["Portico"],"relation":{},"ISSN":["1932-8486","1932-8494"],"issn-type":[{"value":"1932-8486","type":"print"},{"value":"1932-8494","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,2]]}}}