{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T04:48:43Z","timestamp":1772945323443,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,4,4]],"date-time":"2014-04-04T00:00:00Z","timestamp":1396569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Anatomical Record"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Previously, the different monochromatic lights have been demonstrated to affect splenocyte proliferation and melatonin (MEL) secretion in broilers. The present study was designed to evaluate the effects of different monochromatic lights on the development and immune function of broiler cecal tonsils, and to disclose the mechanisms underlying these phenomena. A total of 185 broilers (P0) including intact, sham\u2010operated, and pinealectomized groups were exposed to blue light (BL), green light (GL), red light (RL), and white light (WL) by a light\u2010emitting diode system for 14 days. Compared with RL groups, the GL in the intact and sham\u2010operated groups showed larger follicle areas (66.70%), higher percentages of proliferating cell nuclear antigen (PCNA)\u2010positive cells (33.33%), increased numbers of IgA<jats:sup>+<\/jats:sup> cells (48.60%), and increased antioxidase activity (33.33%\u201361.37%), whereas, the density of iNOS and MDA content in GL were lower (43.63%\u201354.43%) than that of RL. In contrast, after pinealectomy, the area of follicles, the percentage of PCNA\u2010positive cells, the number of IgA<jats:sup>+<\/jats:sup> cells, and the antioxidase activity decreased in the different light treatments, but the density of iNOS and MDA content increased substantially. There was no significant difference in these parameters between broilers exposed to GL and other lights (<jats:italic>P<\/jats:italic> = 0.085\u20131.000). The results suggested that the enhanced effects of GL on the development and immune function of cecal tonsils in young broilers were mediated by elevated antioxidative status via up\u2010regulation of MEL. Anat Rec, 297:1331\u20131337, 2014. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ar.22909","type":"journal-article","created":{"date-parts":[[2014,6,7]],"date-time":"2014-06-07T01:14:04Z","timestamp":1402103644000},"page":"1331-1337","source":"Crossref","is-referenced-by-count":11,"title":["Role of Monochromatic Light on Development of Cecal Tonsil in Young Broilers"],"prefix":"10.1002","volume":"297","author":[{"given":"J.","family":"Li","sequence":"first","affiliation":[{"name":"Laboratory of Anatomy of Domestic Animal, College of Animal Medicine China Agricultural University Beijing 100193 China"},{"name":"Department of Veterinary Medicine College of Animal Sciences, Zhejiang University Hangzhou 310058 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Wang","sequence":"additional","affiliation":[{"name":"Laboratory of Anatomy of Domestic Animal, College of Animal Medicine China Agricultural University Beijing 100193 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Cao","sequence":"additional","affiliation":[{"name":"Laboratory of Anatomy of Domestic Animal, College of Animal Medicine China Agricultural University Beijing 100193 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.L.","family":"Dong","sequence":"additional","affiliation":[{"name":"Laboratory of Anatomy of Domestic Animal, College of Animal Medicine China Agricultural University Beijing 100193 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.X.","family":"Chen","sequence":"additional","affiliation":[{"name":"Laboratory of Anatomy of Domestic Animal, College of Animal Medicine China Agricultural University Beijing 100193 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-305X(02)00076-9"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.3382\/japr.2007-00043"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079451003786105"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1567-5769(02)00088-7"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2011.00866.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-012-9330-z"},{"key":"e_1_2_5_8_1","volume-title":"Avian Biology. 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