{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:21:11Z","timestamp":1788870071074,"version":"build-2803163510"},"reference-count":138,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T00:00:00Z","timestamp":1424131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007660","name":"University of Antwerp","doi-asserted-by":"crossref","award":["TOP-BOF 22292"],"award-info":[{"award-number":["TOP-BOF 22292"]}],"id":[{"id":"10.13039\/501100007660","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Anatomical Record"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The gastrointestinal (GI) tract, just like the skin and the airways, is constantly exposed to both harmless and pathogenic organisms and hence requires a tightly regulated immune homeostasis to function properly. A central role in the regulation of this balance is played by the dendritic cells (DCs), a heterogeneous population of antigen\u2010presenting cells that can be further divided into distinct subsets with different functions depending on the tissue they reside in. In recent years, the DC population in the lamina propria (LP) of the intestine has emerged as a key player in immune surveillance. Given the extensive innervation of the GI mucosa, these DC subsets possibly are also regulated by interactions with neuronal components. Current knowledge, be it still fragmentary, indicates that dysregulation of this neuroimmune communication leads to the onset of pathological disorders. The present review article deals with the identification and interaction of distinct subtypes of mouse intestinal LP DCs with elements of the enteric nervous system (ENS) in normal and inflammatory conditions. Furthermore, the question is addressed whether any parallels can be drawn between intestinal LP DCs and DCs residing in the skin and lung in order to gain a better insight into common or clearly distinct mechanistic pathways and the possible impact of the mucosal components in the microenvironment. The exact way in which the ENS is serving its immunomodulatory roles in the GI tract is still largely unknown, although there are significant indications for a crosstalk between LP DCs and components of the ENS. This review clearly shows that in the three different organ systems the same neurotransmitters (i.e., SP, CGRP, and VIP) reoccur, serving similar functions. Mechanistic lessons learned from other organ systems, such as the skin and lung, may be of substantial help in further exploring the nature of the neuroimmune communication between GI innervation and LP DCs. Anat Rec, 298:903\u2013916, 2015. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ar.23106","type":"journal-article","created":{"date-parts":[[2015,1,23]],"date-time":"2015-01-23T08:25:30Z","timestamp":1422001530000},"page":"903-916","source":"Crossref","is-referenced-by-count":6,"title":["Identification and Putative Roles of Distinct Subtypes of Intestinal Dendritic Cells in Neuroimmune Communication: What can be Learned from Other Organ Systems?"],"prefix":"10.1002","volume":"298","author":[{"given":"Katrien","family":"Alpaerts","sequence":"first","affiliation":[{"name":"Laboratory of Cell biology and Histology Department of Veterinary Sciences University of Antwerp Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roeland","family":"Buckinx","sequence":"additional","affiliation":[{"name":"Laboratory of Cell biology and Histology Department of Veterinary Sciences University of Antwerp Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Adriaensen","sequence":"additional","affiliation":[{"name":"Laboratory of Cell biology and Histology Department of Veterinary Sciences University of Antwerp Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Van Nassauw","sequence":"additional","affiliation":[{"name":"Laboratory of Human Anatomy and Embryology Faculty of Medicine and Health Sciences University of Antwerp Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Pierre","family":"Timmermans","sequence":"additional","affiliation":[{"name":"Laboratory of Cell biology and Histology Department of Veterinary Sciences University of Antwerp Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,17]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2010.79"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000047279.42427.6D"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2012.113"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2008.01.019"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.18.8323"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.12.6466"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07240"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/32588"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1961.80"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2009.08.010"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.6.2417"},{"key":"e_1_2_3_13_1","first-page":"119","article-title":"The epidermis: a sensory tissue","volume":"18","author":"Boulais N","year":"2008","journal-title":"Eur J Dermatol"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1529-8019.2003.01621.x"},{"key":"e_1_2_3_15_1","first-page":"35","article-title":"Intestinal CD103\u2010dendritic cells migrate in lymph and prime effector T cells","volume":"137","author":"Cerovic V","year":"2012","journal-title":"Immunology"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1937-6448(08)01602-X"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.11.006"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2009.00878.x"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2012.09.018"},{"key":"e_1_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070590"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-10-37"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.11.6861"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-1548fje"},{"key":"e_1_2_3_24_1","doi-asserted-by":"crossref","first-page":"3629","DOI":"10.4049\/jimmunol.163.7.3629","article-title":"Vasoactive intestinal peptide and pituitary adenylate cyclase\u2010activating polypeptide stimulate the induction of Th2 responses by up\u2010regulating B7.2 expression","volume":"163","author":"Delgado M","year":"1999","journal-title":"Journal of Immunology"},{"key":"e_1_2_3_25_1","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.4049\/jimmunol.163.6.3071","article-title":"Vasoactive intestinal peptide synergizes with TNF\u2010alpha in inducing human dendritic cell maturation","volume":"163","author":"Delneste Y","year":"1999","journal-title":"J Immunol"},{"key":"e_1_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1511"},{"key":"e_1_2_3_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11809"},{"key":"e_1_2_3_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-011-8219-9"},{"key":"e_1_2_3_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2011.08.030"},{"key":"e_1_2_3_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-010-0219-3"},{"key":"e_1_2_3_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1992.tb22779.x"},{"key":"e_1_2_3_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2183"},{"key":"e_1_2_3_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.01.009"},{"key":"e_1_2_3_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/icb.2012.79"},{"key":"e_1_2_3_35_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1004036"},{"key":"e_1_2_3_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2012.32"},{"key":"e_1_2_3_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1996.tb01191.x"},{"key":"e_1_2_3_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.02.028"},{"key":"e_1_2_3_39_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.10.023"},{"key":"e_1_2_3_40_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.47.3.387"},{"key":"e_1_2_3_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2009.00880.x"},{"key":"e_1_2_3_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2012.03964.x"},{"key":"e_1_2_3_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20129"},{"key":"e_1_2_3_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201040498"},{"key":"e_1_2_3_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-13-94"},{"key":"e_1_2_3_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.01.016"},{"key":"e_1_2_3_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2010.02528.x"},{"key":"e_1_2_3_48_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.05.013"},{"key":"e_1_2_3_49_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2003.037325"},{"key":"e_1_2_3_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2009.00885.x"},{"key":"e_1_2_3_51_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20091964"},{"key":"e_1_2_3_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/363159a0"},{"key":"e_1_2_3_53_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.9.5829"},{"key":"e_1_2_3_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0812247106"},{"key":"e_1_2_3_55_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200107000-00013"},{"key":"e_1_2_3_56_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20080414"},{"key":"e_1_2_3_57_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.5.3019"},{"key":"e_1_2_3_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2012.07.009"},{"key":"e_1_2_3_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2006.03197.x"},{"key":"e_1_2_3_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2007.02.036"},{"key":"e_1_2_3_61_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004204"},{"key":"e_1_2_3_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2005.04.004"},{"key":"e_1_2_3_63_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1102521"},{"key":"e_1_2_3_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01296290"},{"key":"e_1_2_3_65_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.173.10.6082"},{"key":"e_1_2_3_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)80068-P"},{"key":"e_1_2_3_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200939957"},{"key":"e_1_2_3_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4141(199912)29:12<3815::AID-IMMU3815>3.0.CO;2-#"},{"key":"e_1_2_3_69_1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1159\/000155087","article-title":"Lung dendritic cells: targets for therapy in allergic disease","volume":"94","author":"Lambrecht BN","year":"2008","journal-title":"Chem Immunol Allergy"},{"key":"e_1_2_3_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2009.08.008"},{"key":"e_1_2_3_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01959006"},{"key":"e_1_2_3_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2010.10.028"},{"key":"e_1_2_3_73_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.23.021704.115633"},{"key":"e_1_2_3_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2003.08.039"},{"key":"e_1_2_3_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2013.01.007"},{"key":"e_1_2_3_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(98)00216-1"},{"key":"e_1_2_3_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-09550-9_1"},{"key":"e_1_2_3_78_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002588"},{"key":"e_1_2_3_79_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-302550"},{"key":"e_1_2_3_80_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.03.043"},{"key":"e_1_2_3_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(98)00271-9"},{"key":"e_1_2_3_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10863"},{"key":"e_1_2_3_83_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-12-180646"},{"key":"e_1_2_3_84_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1100028"},{"key":"e_1_2_3_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092130111"},{"key":"e_1_2_3_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-010-8225-z"},{"key":"e_1_2_3_87_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.10.001"},{"key":"e_1_2_3_88_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1145697"},{"key":"e_1_2_3_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2008.06.012"},{"key":"e_1_2_3_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12100"},{"key":"e_1_2_3_91_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.5138"},{"key":"e_1_2_3_92_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-07-2903"},{"key":"e_1_2_3_93_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201040557"},{"key":"e_1_2_3_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2007.01.003"},{"key":"e_1_2_3_95_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.10.6695"},{"key":"e_1_2_3_96_1","doi-asserted-by":"publisher","DOI":"10.2174\/187152410790780154"},{"key":"e_1_2_3_97_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0903878"},{"key":"e_1_2_3_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2010.05.013"},{"key":"e_1_2_3_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2012.02.004"},{"key":"e_1_2_3_100_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1103096"},{"key":"e_1_2_3_101_1","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0022-3565(24)37636-0","article-title":"Calcitonin gene\u2010related peptide mediates the protective effect of sensory nerves in a model of colonic injury","volume":"286","author":"Reinshagen M","year":"1998","journal-title":"J Pharmacol Exp Therap"},{"key":"e_1_2_3_102_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI39134"},{"key":"e_1_2_3_103_1","doi-asserted-by":"publisher","DOI":"10.1078\/0065-1281-00688"},{"key":"e_1_2_3_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13199"},{"key":"e_1_2_3_105_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20101387"},{"key":"e_1_2_3_106_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2011.03822.x"},{"key":"e_1_2_3_107_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20041789"},{"key":"e_1_2_3_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2009.00886.x"},{"key":"e_1_2_3_109_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2011.00786.x"},{"key":"e_1_2_3_110_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i33.3761"},{"key":"e_1_2_3_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2013.129"},{"key":"e_1_2_3_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.07.014"},{"key":"e_1_2_3_113_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20091925"},{"key":"e_1_2_3_114_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.12.6128"},{"key":"e_1_2_3_115_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1110076108"},{"key":"e_1_2_3_116_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2340\/0001555553112","article-title":"Apposition of mononuclear cells to langerhans cells in contact allergic reactions","volume":"53","author":"Silberberg I","year":"1973","journal-title":"An ultrastructural study. Acta Dermato\u2010Venereol"},{"key":"e_1_2_3_117_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161210790963814"},{"key":"e_1_2_3_118_1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/978-1-4615-1971-3_32","article-title":"Expression of neuropeptides on human epidermal Langerhans cells","volume":"378","author":"Staniek V","year":"1995","journal-title":"Adv Exp Med Biol"},{"key":"e_1_2_3_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004030050194"},{"key":"e_1_2_3_120_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-100311-102839"},{"key":"e_1_2_3_121_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.137.5.1142"},{"key":"e_1_2_3_122_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.21.120601.141040"},{"key":"e_1_2_3_123_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.10.5132"},{"key":"e_1_2_3_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-4579(99)00256-7"},{"key":"e_1_2_3_125_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12324502"},{"key":"e_1_2_3_126_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070602"},{"key":"e_1_2_3_127_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.176.4.2161"},{"key":"e_1_2_3_128_1","doi-asserted-by":"publisher","DOI":"10.1002\/immu.200390017"},{"key":"e_1_2_3_129_1","first-page":"301","article-title":"Substance P receptor expression in patients with inflammatory bowel disease","volume":"41","author":"ter Beek WP","year":"2007","journal-title":"Determination by three different techniques, i.e., storage phosphor autoradiography, RT\u2010PCR and immunohistochemistry. Neuropeptides"},{"key":"e_1_2_3_130_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2009.00872.x"},{"key":"e_1_2_3_131_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12337516"},{"key":"e_1_2_3_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80160-0"},{"key":"e_1_2_3_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2009.06.025"},{"key":"e_1_2_3_134_1","doi-asserted-by":"publisher","DOI":"10.1177\/002215540104900608"},{"key":"e_1_2_3_135_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2007-0087OC"},{"key":"e_1_2_3_136_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0045951"},{"key":"e_1_2_3_137_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.04686.x"},{"key":"e_1_2_3_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2006.09.009"},{"key":"e_1_2_3_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature06005"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Far.23106","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.23106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T18:36:11Z","timestamp":1759948571000},"score":1,"resource":{"primary":{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/10.1002\/ar.23106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,17]]},"references-count":138,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1002\/ar.23106"],"URL":"https:\/\/doi.org\/10.1002\/ar.23106","archive":["Portico"],"relation":{},"ISSN":["1932-8486","1932-8494"],"issn-type":[{"value":"1932-8486","type":"print"},{"value":"1932-8494","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,17]]}}}