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The effects of treatment were verified by recordings of auditory brainstem response and distortion product otoacoustic emission. Three or 8 days after acoustic trauma, rats received unilateral injections of an aqueous solution of the retrograde neuronal tracer Fluorogold (FG) into the scala tympani to identify OC neurons (OCN). Five days after FG injection, brains were perfusion\u2010fixed, and brainstem sections were cut and analyzed with respect to FG\u2010labeled neurons. We found that, in both groups, numbers of OCN were similar to that of controls. The incubation of a second set of sections with antibodies against choline\u2010acetyltransferase (the enzyme responsible for acetylcholine synthesis) showed the cholinergic neurons of the brainstem, however, without suggesting differences between groups. Our study, the first to investigate noise trauma effects on identified OCN, revealed that no visible alterations occurred in 2 weeks following trauma, neither in identified OCN nor in choline\u2010acetyltransferase\u2010immunofluorescence. At this time, auditory brainstem response and distortion product otoacoustic emission measurements showed severe signs of hearing loss. The mechanisms leading to hearing loss upon noise trauma apparently do not involve degeneration of OCN. Anat Rec, 299:103\u2013110, 2016. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ar.23277","type":"journal-article","created":{"date-parts":[[2015,10,9]],"date-time":"2015-10-09T21:50:01Z","timestamp":1444427401000},"page":"103-110","source":"Crossref","is-referenced-by-count":4,"title":["Absence of Early Neuronal Death in the Olivocochlear System Following Acoustic Overstimulation"],"prefix":"10.1002","volume":"299","author":[{"given":"Stefan","family":"Reuss","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine University Medical Center, Johannes Gutenberg\u2010University Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Closhen","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Cell Biology University Medical Center, Johannes Gutenberg\u2010University Mainz 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