{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T21:47:43Z","timestamp":1759960063200,"version":"build-2065373602"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T00:00:00Z","timestamp":1541721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["355316"],"award-info":[{"award-number":["355316"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anatomypubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Anatomical Record"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Enteropathogenic <jats:italic>Escherichia coli<\/jats:italic> (EPEC), <jats:italic>Salmonella typhimurium<\/jats:italic>, and <jats:styled-content style=\"fixed-case\"><jats:italic>Listeria monocytogenes<\/jats:italic><\/jats:styled-content> usurp the actin cytoskeleton for their attachment, internalization and transport within and amongst infected cells. To try to gain a greater understanding of the molecular components utilized by these microbes during their infections we previously concentrated actin\u2010rich structures generated during EPEC infections (called pedestals) and identified the heat shock cognate 70 protein (Hsc70) as a potential candidate. This multifunctional protein classically acts as a chaperone for the proper folding of a variety of proteins and is involved in uncoating clathrin from coated pits. Here we demonstrated that Hsc70 is recruited to actin structures generated during EPEC, <jats:italic>Listeria<\/jats:italic> and <jats:italic>Salmonella<\/jats:italic> infections, but not to the same location as clathrin. Anat Rec, 301:2095\u20132102, 2018. \u00a9 2018 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ar.23955","type":"journal-article","created":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T13:19:18Z","timestamp":1539350358000},"page":"2095-2102","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Hsc70 is a Component of Bacterially Generated Actin\u2010Rich Structures: An Immunolocalization Study"],"prefix":"10.1002","volume":"301","author":[{"given":"Brittany D.","family":"Walker","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, Centre for Cell Biology, Development, and Disease (C2D2) Simon Fraser University  Burnaby British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Chua","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Centre for Cell Biology, Development, and Disease (C2D2) Simon Fraser 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