{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T20:05:31Z","timestamp":1793217931882,"version":"4.5.0"},"reference-count":65,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T00:00:00Z","timestamp":1635120000000},"content-version":"am","delay-in-days":339,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T00:00:00Z","timestamp":1605830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["NSF EAR 1631684"],"award-info":[{"award-number":["NSF EAR 1631684"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anatomypubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Anatomical Record"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Cranial nerves are key features of the nervous system and vertebrate body plan. However, little is known about the anatomical relationships and ontogeny of cranial nerves in crocodylians and other reptiles, hampering understanding of adaptations, evolution, and development of special senses, somatosensation, and motor control of cranial organs. Here we share three dimensional (3D) models an of the cranial nerves and cranial nerve targets of embryonic, juvenile, and adult American Alligators (\n                    <jats:italic>Alligator mississippiensis<\/jats:italic>\n                    ) derived from iodine\u2010contrast CT imaging, for the first time, exploring anatomical patterns of cranial nerves across ontogeny. These data reveal the tradeoffs of using contrast\u2010enhanced CT data as well as patterns in growth and development of the alligator cranial nervous system. Though contrast\u2010enhanced CT scanning allows for reconstruction of numerous tissue types in a nondestructive manner, it is still limited by size and resolution. The position of alligator cranial nerves varies little with respect to other cranial structures yet grow at different rates as the skull elongates. These data constrain timing of trigeminal and sympathetic ganglion fusion and reveal morphometric differences in nerve size and path during growth. As demonstrated by these data, alligator cranial nerve morphology is useful in understanding patterns of neurological diversity and distribution, evolution of sensory and muscular innervation, and developmental homology of cranial regions, which in turn, lead to inferences of physiology and behavior.\n                  <\/jats:p>","DOI":"10.1002\/ar.24550","type":"journal-article","created":{"date-parts":[[2020,10,25]],"date-time":"2020-10-25T12:42:45Z","timestamp":1603629765000},"page":"2854-2882","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["A\n                    <scp>\n                      3D ontogenetic atlas of\n                      <i>Alligator mississippiensis<\/i>\n                      cranial nerves and their significance for comparative neurology of reptiles\n                    <\/scp>"],"prefix":"10.1002","volume":"305","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0774-1613","authenticated-orcid":false,"given":"Emily J.","family":"Lessner","sequence":"first","affiliation":[{"name":"Program in Integrative Anatomy, Department of Pathology and Anatomical Sciences University of Missouri School of Medicine  Columbia Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8210-8434","authenticated-orcid":false,"given":"Casey M.","family":"Holliday","sequence":"additional","affiliation":[{"name":"Program in Integrative Anatomy, Department of Pathology and Anatomical Sciences University of Missouri School of Medicine  Columbia Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,20]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Al\u2010HassawiAMA.The osteology and myology of the craniocervical region in squamate reptiles: a comparative study. PhD dissertation University College London;2004."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2009.01202.x"},{"key":"e_1_2_7_4_1","first-page":"367","article-title":"Observations on the narial musculature of Crocodilia and its innervation from the sympathetic system","volume":"87","author":"Bellairs A. A.","year":"1953","journal-title":"Journal of Anatomy"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/476018"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1052020108"},{"key":"e_1_2_7_7_1","unstructured":"CarlisleA WeisbeckerV.2016.A modified STABILITY protocol for accurate retrieval of soft\u2010tissue data from micro\u2010CT scans of IKI\u2010stained specimens. Published online athttps:\/\/dicect.com\/2016\/08\/09\/stability\/ August 9 2016."},{"key":"e_1_2_7_8_1","first-page":"333","article-title":"Temperature tolerances in the American alligator and their bearing on the habits, evolution, and extinction of the dinosaurs","volume":"86","author":"Colbert E. H.","year":"1946","journal-title":"Bulletin of the AMNH"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900270304"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2007.00786.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7998.1975.tb01405.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0137060"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952836903003819"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41559-017-0288-2"},{"key":"e_1_2_7_15_1","first-page":"223","volume-title":"The Structure, Development and Evolution of Reptiles, Symposia of the Zoological Society of London","author":"Ferguson M. W. J.","year":"1984"},{"key":"e_1_2_7_16_1","first-page":"329","volume-title":"Biology of the Reptilia","author":"Ferguson M. W. J.","year":"1985"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04328"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2012.02.013"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.22666"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jzo.12349"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.s2-61.242.137"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1086\/505758"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-8-64"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1525\/auk.2010.09122"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.10524"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1671\/039.029.0330"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062806"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.2307\/2405826"},{"key":"e_1_2_7_29_1","first-page":"256","article-title":"The jaw muscles of the crocodiles and some relating structures of the crocodilian skull","volume":"115","author":"Iordansky N. N.","year":"1964","journal-title":"Antomischer Anzeiger"},{"key":"e_1_2_7_30_1","first-page":"201","volume-title":"Biology of the Reptilia, Vol. 4: Morphology D","author":"Iordansky N. N.","year":"1973"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.5962\/bhl.title.6408"},{"key":"e_1_2_7_32_1","volume-title":"Principals of neural science","author":"Kandel E.","year":"2000"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1163\/156853887X00054"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781420008661.ch3"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1046"},{"key":"e_1_2_7_36_1","volume-title":"Studien \u00fcber die Trigeminus\u2010versorgte Kaumuskulatur der Sauropsiden","author":"Lakjer T.","year":"1926"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.076836"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.24116"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12320"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsos.160356"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/brv.12578"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.4202\/app.00527.2018"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.2307\/1564502"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4687(199701)231:1<53::AID-JMOR5>3.0.CO;2-P"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1052030204"},{"key":"e_1_2_7_46_1","first-page":"257","article-title":"Untersuchungen der Kiefermuskulatur und deren Innervation an Krokodilen","volume":"99","author":"Poglayen\u2010Neuwall I.","year":"1953","journal-title":"Anatomischer Anzeiger"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12539"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.5962\/bhl.title.54967"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.117101"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1096-3642.1993.tb02537.x"},{"key":"e_1_2_7_51_1","volume-title":"Osteology of the reptiles","author":"Romer A. S.","year":"1956"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1080\/02724634.1999.10011200"},{"key":"e_1_2_7_53_1","first-page":"101","volume-title":"Biology of the Reptilia","author":"Schumacher G. H.","year":"1973"},{"key":"e_1_2_7_54_1","first-page":"2036","article-title":"Ontogeny of bite force in a validated biomechanical model of the American alligator","volume":"220","author":"Sellers K. C.","year":"2017","journal-title":"The Company of Biologists"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.3897\/zookeys.28.325"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.16965\/ijar.2015.206"},{"key":"e_1_2_7_57_1","first-page":"254","article-title":"Studien zur Kenntniss des Wirbeltierkopfes. 1. Das Chondrocranium in Crocodilus mit Ber\u00fccksichtigund der Gehirnnerven und Kopfgef\u00e4sse","volume":"50","author":"Shiino K.","year":"1914","journal-title":"Anatomische Hefte"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/417241a"},{"key":"e_1_2_7_59_1","first-page":"159","article-title":"A comparative study of the nictitating membrane of birds and mammals","volume":"62","author":"Stibbe E. P.","year":"1928","journal-title":"Journal of Anatomy"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024935"},{"key":"e_1_2_7_61_1","first-page":"171","volume-title":"Sensory neurons: Diversity, development, and plasticity","author":"Vogel K. S.","year":"1992"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2015.03.007"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.5456"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1820967116"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1050920205"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084321"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.24550","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ar.24550","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/am-pdf\/10.1002\/ar.24550","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.24550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T13:13:18Z","timestamp":1759929198000},"score":1,"resource":{"primary":{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/10.1002\/ar.24550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,20]]},"references-count":65,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/ar.24550"],"URL":"https:\/\/doi.org\/10.1002\/ar.24550","archive":["Portico"],"relation":{},"ISSN":["1932-8486","1932-8494"],"issn-type":[{"value":"1932-8486","type":"print"},{"value":"1932-8494","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,20]]},"assertion":[{"value":"2020-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}