{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:30:05Z","timestamp":1786977005485,"version":"build-2736575974"},"reference-count":61,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005966","name":"Leakey Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005966","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anatomypubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Anatomical Record"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In the current study, we detail, through the analysis of immunohistochemically stained sections, the morphology and nuclear parcellation of the serotonergic neurons present in the brainstem of a lar gibbon and a chimpanzee. In general, the neuronal morphology and nuclear organization of the serotonergic system in the brains of these two species of apes follow that observed in a range of Eutherian mammals and are specifically very similar to that observed in other species of primates. In both of the apes studied, the serotonergic nuclei could be readily divided into two distinct groups, a rostral and a caudal cluster, which are found from the level of the decussation of the superior cerebellar peduncle to the spinomedullary junction. The rostral cluster is comprised of the caudal linear, supralemniscal, and median raphe nuclei, as well as the six divisions of the dorsal raphe nuclear complex. The caudal cluster contains several distinct nuclei and nuclear subdivisions, including the raphe magnus nucleus and associated rostral and caudal ventrolateral (CVL) serotonergic groups, the raphe pallidus, and raphe obscurus nuclei. The one deviation in organization observed in comparison to other primate species is an expansion of both the number and distribution of neurons belonging to the lateral division of the dorsal raphe nucleus in the chimpanzee. It is unclear whether this expansion occurs in humans, thus at present, this expansion sets the chimpanzee apart from other primates studied to date.<\/jats:p>","DOI":"10.1002\/ar.24795","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T20:53:52Z","timestamp":1633380832000},"page":"1500-1515","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Nuclear organization of serotonergic neurons in the brainstems of a lar gibbon and a chimpanzee"],"prefix":"10.1002","volume":"305","author":[{"given":"Victoria M.","family":"Williams","sequence":"first","affiliation":[{"name":"School of Anatomical Sciences, Faculty of Health Sciences University of the Witwatersrand  Johannesburg Republic of South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adhil","family":"Bhagwandin","sequence":"additional","affiliation":[{"name":"School of Anatomical Sciences, Faculty of Health Sciences University of the Witwatersrand  Johannesburg Republic of South Africa"},{"name":"Division of Clinical Anatomy and Biological Anthropology, Department of Human Biology University of Cape Town  Cape Town South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Swiegers","sequence":"additional","affiliation":[{"name":"School of Anatomical Sciences, Faculty of Health Sciences University of the Witwatersrand  Johannesburg Republic of South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mads F.","family":"Bertelsen","sequence":"additional","affiliation":[{"name":"Centre for Zoo and Wild Animal Health, Copenhagen Zoo  Frederiksberg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therese","family":"H\u00e5rd","sequence":"additional","affiliation":[{"name":"Bor\u00e5s Zoo  Bor\u00e5s Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chet C.","family":"Sherwood","sequence":"additional","affiliation":[{"name":"Department of Anthropology and Center for the Advanced Study of Human Paleobiology The George Washington University  Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1881-2854","authenticated-orcid":false,"given":"Paul R.","family":"Manger","sequence":"additional","affiliation":[{"name":"School of Anatomical Sciences, Faculty of Health Sciences University of the Witwatersrand  Johannesburg Republic of South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"407","article-title":"The primate serotonergic system: A review of human and animal studies and a report on Macaca fascicularis","volume":"43","author":"Azmitia E. 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