{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T20:26:09Z","timestamp":1781641569973,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T00:00:00Z","timestamp":1668556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["anatomypubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Anatomical Record"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The morphologies of the fetal tentorium cerebelli (TC) and brain influence each other during development. This study aimed to analyze and more comprehensively understand the three\u2010dimensional morphogenesis of the TC and fetal brain. We examined magnetic resonance imaging from 64 embryonic and fetal specimens (crown\u2010rump length range, 9.2\u2013225\u2009mm). During the embryonic period, the lateral folds of the TC elongated to traverse the middle part of the midbrain. The TC and falx cerebri appeared separated, and no invaginations at the parieto\u2010occipital region were observed. In the early fetal period, the cerebrum covered approximately half of the midbrain. The separation of the dural limiting layer at the parieto\u2010occipital region widened from the posterior cerebrum to the cranial cerebellum. The lateral folds of the TC were spread between its tip, continuous with the falx cerebri, and its base plane, located between the midbrain and rostral hindbrain. Differences in the TC components' growth directions gradually diminished as the cerebrum covered the midbrain. We observed rotation of the TC at its median section according to its growth, which ceased in the middle fetal period. The brainstem and cerebellum extended inferiorly via differential growth, with the cerebrum covering them superiorly. The morphology of the TC curved to conform to the cerebellar and cerebral surfaces. Our present study suggests that factors affecting TC morphology differ between the early and middle fetal periods. Present data provided a more comprehensive view of TC formation according to developmental stage.<\/jats:p>","DOI":"10.1002\/ar.25110","type":"journal-article","created":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T12:00:25Z","timestamp":1667476825000},"page":"515-526","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Tentorium cerebelli formation during human embryonic and early fetal development"],"prefix":"10.1002","volume":"306","author":[{"given":"Chieko","family":"Matsunari","sequence":"first","affiliation":[{"name":"Human Health Science, Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9895-0500","authenticated-orcid":false,"given":"Toru","family":"Kanahashi","sequence":"additional","affiliation":[{"name":"Human Health Science, Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0331-3008","authenticated-orcid":false,"given":"Hiroki","family":"Otani","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology, Faculty of Medicine Shimane University  Izumo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirohiko","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Systems Science, Graduate School of Informatics Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8194-6927","authenticated-orcid":false,"given":"Shigehito","family":"Yamada","sequence":"additional","affiliation":[{"name":"Human Health Science, Graduate School of Medicine Kyoto University  Kyoto Japan"},{"name":"Congenital Anomaly Research Center, Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2312-5677","authenticated-orcid":false,"given":"Tomohisa","family":"Okada","sequence":"additional","affiliation":[{"name":"Human Brain Research Center, Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9660-9384","authenticated-orcid":false,"given":"Tetsuya","family":"Takakuwa","sequence":"additional","affiliation":[{"name":"Human Health Science, Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-012-1744-6"},{"key":"e_1_2_12_3_1","first-page":"359","article-title":"Uber die Entwicklung und Differenzierung der hullen des Menschlichen Gehirnes","volume":"83","author":"Hochstetter F.","year":"1939","journal-title":"Morphologisches Jahrbuch"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0021-8782.2001.00017.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.13760"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091580407"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.24796"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02204753"},{"key":"e_1_2_12_9_1","first-page":"463","article-title":"Developmental morphology of the subarachnoid space, brain vasculature, and contiguous structures, and the cause of the Chiari II malformation","volume":"13","author":"McLone D. 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