{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:18:39Z","timestamp":1773008319147,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:00:00Z","timestamp":1772841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:00:00Z","timestamp":1772841600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008994","name":"Universidade de Bras\u00edlia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008994","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anatomypubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Anatomical Record"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid\n                    <jats:italic>Bothrops moojeni<\/jats:italic>\n                    , based on a sample of seven individuals. Our results indicate that brain morphology undergoes significant size\u2010related reshaping during growth: absolute measures revealed strong positive scaling of brain length, cerebral hemisphere length, cerebellum length, and medulla oblongata length with body and head size. However, when expressed relative to overall brain dimensions, most regions exhibited weak or no association with size, indicating relatively stable proportional relationships, while the olfactory bulbs and medulla oblongata became relatively more developed in adults. These relative increases likely reflect increased demands for chemosensory processing and autonomic regulation as individuals shift from consuming ectothermic to endothermic prey. In contrast, structures such as the cerebellum width, posterior colliculi, and epiphysis remained stable across ontogeny, suggesting conserved functional roles. Collectively, these findings reveal a mosaic pattern of brain development in females of\n                    <jats:italic>B. moojeni<\/jats:italic>\n                    , in which certain regions expand preferentially while others remain constrained, underscoring that encephalic growth is shaped by functional priorities and evolutionary trade\u2010offs, consistent with patterns described in other vertebrates.\n                  <\/jats:p>","DOI":"10.1002\/ar.70171","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:19:28Z","timestamp":1773001168000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Much more than their fangs: Macroscopic anatomy of the brain of\n                    <i>Bothrops moojeni<\/i>\n                    Hoge 1966 (Squamata, Serpentes, Viperidae)"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5806-0386","authenticated-orcid":false,"given":"Paula","family":"Ara\u00fajo","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s gradua\u00e7\u00e3o em Zoologia, Instituto de Ci\u00eancias Biol\u00f3gicas Universidade de Bras\u00edlia  Bras\u00edlia Brazil"},{"name":"Laborat\u00f3rio de Anatomia Comparada de Vertebrados, Departamento de Ci\u00eancias Fisiol\u00f3gicas, Instituto de Biologia Universidade de Bras\u00edlia  Bras\u00edlia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falio C\u00e9sar Costa","family":"de Souza","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s gradua\u00e7\u00e3o em Zoologia, Instituto de Ci\u00eancias Biol\u00f3gicas Universidade de Bras\u00edlia  Bras\u00edlia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0193-4011","authenticated-orcid":false,"given":"Angele","family":"Martins","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s gradua\u00e7\u00e3o em Zoologia, Instituto de Ci\u00eancias Biol\u00f3gicas Universidade de Bras\u00edlia  Bras\u00edlia Brazil"},{"name":"Laborat\u00f3rio de Anatomia Comparada de Vertebrados, Departamento de Ci\u00eancias Fisiol\u00f3gicas, Instituto de Biologia Universidade de Bras\u00edlia  Bras\u00edlia Brazil"},{"name":"Departamento de Vertebrados Museu Nacional\/UFRJ  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.25142"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2994\/SAJH-D-16-00047.1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jeb.13032"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmammal\/gyz043"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.21617"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2011.05959.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/9781108938891.024"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.10926"},{"key":"e_1_2_8_10_1","first-page":"39","article-title":"First documented cases of cannibalism in Bothrops moojeni Hoge, 1966 from the Cerrado of central Brazil","volume":"18","author":"Falc\u00e3o B. B.","year":"2025","journal-title":"Herpetology Notes"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0901780106"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1071\/MU13034"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1525\/9780520935433"},{"key":"e_1_2_8_14_1","first-page":"341","article-title":"Hoge 1966 (Serpentes: Viperidae)","volume":"63","author":"Hoge","year":"1966","journal-title":"Anais da Academia Brasileira de Ci\u00eancia"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12862-015-0358-5"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.24676"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2020.03.060"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.zool.2021.125926"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1477200007002290"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.25672"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adi6888"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13405-w"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.3897\/vz.73.e98170"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jzs.12316"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00435-018-0409-8"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0219661"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00435-020-00492-3"},{"key":"e_1_2_8_28_1","first-page":"307","volume-title":"Biology of the vipers","author":"Martins M. A. R. C. I. O.","year":"2002"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952836901001030"},{"key":"e_1_2_8_30_1","volume-title":"Anatomie de Latimeria chalumnae. 2. Syst\u00e8me nerveux et organes des sens","author":"Millot J.","year":"1965"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1206\/862.1"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2015.02.049"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.2994\/SAJH-D-19-00120.1"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1670\/120-02a"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12799"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.23191"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1159\/000341161"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.10014"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/czoolo\/61.2.281"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1159\/000455183"},{"key":"e_1_2_8_41_1","first-page":"89","volume-title":"Venomous snakes: ecology, evolution and snakebite","author":"Salom\u00e3o M. D. G.","year":"1997"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1017\/9781108938891.019"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-021-02340-6"},{"key":"e_1_2_8_44_1","volume-title":"Uber das optische System im Gehirn squamater Reptilien","author":"Senn D. G.","year":"1966"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcz.2017.11.001"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolinnean\/blad084"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41559-018-0632-1"},{"key":"e_1_2_8_48_1","unstructured":"Uetz P. Freed P. Aguilar R. Reyes F. Kudera J. &Hossek J.(2025).The Reptile Database.http:\/\/www.reptile-database.org"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsbl.2010.0220"},{"key":"e_1_2_8_50_1","first-page":"709","volume-title":"The venomous reptiles of the western hemisphere","author":"Warrell D. A.","year":"2004"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1159\/000316031"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0216148"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ympev.2015.10.009"}],"container-title":["The Anatomical Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.70171","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ar.70171","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ar.70171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:19:31Z","timestamp":1773001171000},"score":1,"resource":{"primary":{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/10.1002\/ar.70171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,7]]},"references-count":52,"alternative-id":["10.1002\/ar.70171"],"URL":"https:\/\/doi.org\/10.1002\/ar.70171","archive":["Portico"],"relation":{},"ISSN":["1932-8486","1932-8494"],"issn-type":[{"value":"1932-8486","type":"print"},{"value":"1932-8494","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,7]]},"assertion":[{"value":"2025-10-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ar.70171"}}