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SARs play a role in controlling breathing pattern, airway smooth muscle tone, systemic vascular resistance, and heart rate. Both anatomical and physiological studies support the contention that SARs, by their close association with airway smooth muscle, continuously sense the tension within the myoelastic components of the airways caused by lung inflation, smooth muscle contraction, and\/or tethering of small intrapulmonary airways to the lung parenchyma. As a result, the receptor field location within the tracheobronchial tree of a SAR plays an important role in its discharge pattern, with variations in airway transluminal pressure and airway smooth muscle orientation being important modulating factors. The disruption of airway myoelastic components in various pulmonary diseases would be expected to alter the discharge pattern of SARs, and contribute to changes in breathing pattern and airway smooth muscle tone. Anat Rec Part A 270A:11\u201316, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ar.a.10004","type":"journal-article","created":{"date-parts":[[2002,12,20]],"date-time":"2002-12-20T09:07:53Z","timestamp":1040375273000},"page":"11-16","source":"Crossref","is-referenced-by-count":59,"title":["Functional morphology and physiology of slowly adapting pulmonary stretch receptors"],"prefix":"10.1002","volume":"270A","author":[{"given":"Edward S.","family":"Schelegle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,12,17]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1933.sp003053"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(85)90060-X"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1976.sp011427"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1993.sp019657"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.910030301"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1976.sp011563"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(80)90017-1"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(78)90053-1"},{"key":"e_1_2_3_10_1","series-title":"Handbook of physiology. 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