{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:12:16Z","timestamp":1762078336534},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2003,6,11]],"date-time":"2003-06-11T00:00:00Z","timestamp":1055289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arch Insect Biochem Physiol"],"published-print":{"date-parts":[[2003,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The cytochrome P450 monooxygenases are an important metabolic system whose level of activity can be influenced by several dietary constituents. We examined the effects of six known P450 inducers on the levels of total cytochromes P450, cytochrome b<jats:sub>5<\/jats:sub>, and six monooxygenase activities in adult German cockroaches. In addition, the levels of CYP6L1 and CYP9E2 mRNA were also investigated. Phenobarbital treatment resulted in increases in total cytochromes P450 and metabolism of three resorufin analogues, but not CYP6L1 nor CYP9E2 mRNA. There was no significant effect of the other five inducers on any of the monooxygenase parameters we measured. In comparison with other insects, the German cockroach seems unusually refractory to most inducing agents. Arch. Insect Biochem. Physiol. 53:119\u2013124, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/arch.10089","type":"journal-article","created":{"date-parts":[[2003,6,12]],"date-time":"2003-06-12T10:10:35Z","timestamp":1055412635000},"page":"119-124","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Induction of P450 monooxygenases in the German cockroach, <i>Blattella germanica<\/i> L."],"prefix":"10.1002","volume":"53","author":[{"given":"Danielle","family":"Brown","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhimou","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey G.","family":"Scott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,6,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5461.2185"},{"key":"e_1_2_1_3_1","first-page":"311","article-title":"Induction of cytochrome P450 activities in Drosophila melanogaster strains susceptible or resistant to insecticides","volume":"121","author":"Amichot M","year":"1998","journal-title":"Comp Biochem Physiol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ento.47.091201.145224"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0048-3575(73)90066-7"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/oso\/9780195064957.003.0004","volume-title":"Understanding and controlling the German cockroach","author":"Brenner RJ","year":"1995"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0020-1790(83)90068-9"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200038060-00003"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-2797(81)90127-7"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(88)90066-5"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0048-3575(72)90026-0"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/jee\/82.6.1559"},{"key":"e_1_2_1_14_1","volume-title":"Cytochromes P450 structure, function and mechanism","author":"Lewis DFV","year":"1996"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(20)82244-3"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1076781"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/03602539709037591"},{"key":"e_1_2_1_18_1","first-page":"35","volume-title":"Handbook of genetics","author":"Ross MH","year":"1975"},{"key":"e_1_2_1_19_1","volume-title":"Molecular cloning: a laboratory manual","author":"Sambrook J","year":"1989"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1997.2055"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1006\/pest.1997.2311"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0965-1748(97)00060-X"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/arch.940240102"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6327(1996)31:3<313::AID-ARCH6>3.0.CO;2-Y"},{"key":"e_1_2_1_25_1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.2144\/99261bm06","article-title":"Normalization of RNA hybridization signals by means of SYBR Green II\u2010stained 28S or 18S ribosomal RNA and phosphor imager","volume":"26","author":"Spiess A\u2010N","year":"1998","journal-title":"BioTechniques"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1119(00)00533-3"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(93)90006-E"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1006\/pest.1996.0006"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1006\/pest.1994.1046"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0965-1748(00)00116-8"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1119(01)00529-7"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0048-3575(02)00021-4"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0048-3575(73)90098-9"}],"container-title":["Archives of Insect Biochemistry and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Farch.10089","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/arch.10089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T06:42:09Z","timestamp":1700203329000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/arch.10089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6,11]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,7]]}},"alternative-id":["10.1002\/arch.10089"],"URL":"https:\/\/doi.org\/10.1002\/arch.10089","archive":["Portico"],"relation":{},"ISSN":["0739-4462","1520-6327"],"issn-type":[{"value":"0739-4462","type":"print"},{"value":"1520-6327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6,11]]},"assertion":[{"value":"2002-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-03-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-06-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}