{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:21:24Z","timestamp":1760782884348},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,9,23]],"date-time":"2006-09-23T00:00:00Z","timestamp":1158969600000},"content-version":"vor","delay-in-days":5744,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archiv der Pharmazie"],"published-print":{"date-parts":[[1991,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Barbiturates <jats:bold>3<\/jats:bold> as possible antimicrobial agents were obtained by reacting the <jats:italic>N,N<\/jats:italic>\u2032\u2010disubstituted urea <jats:bold>1a<\/jats:bold> or the thiourea analogues <jats:bold>1b,c<\/jats:bold> with the magic malonates <jats:bold>2a,b<\/jats:bold>. On the other hand, reaction of <jats:bold>1a<\/jats:bold> with ethoxycarbonyl isocyanate (<jats:bold>4<\/jats:bold>) yielded the substituted <jats:italic>s<\/jats:italic>\u2010triazine\u20102,4,6(1<jats:italic>H<\/jats:italic>,3<jats:italic>H<\/jats:italic>,5<jats:italic>H<\/jats:italic>)\u2010trione <jats:bold>5<\/jats:bold>. The reaction of <jats:bold>4<\/jats:bold> with 2\u2010aminomethyl\u2010benzimidazole (<jats:bold>6<\/jats:bold>) gave the allophanate <jats:bold>7<\/jats:bold> which upon treatment with Na<jats:sub>2<\/jats:sub>CO<jats:sub>3<\/jats:sub> yielded <jats:italic>N<\/jats:italic>\u2010(1<jats:italic>H<\/jats:italic>\u2010benzimidazol\u20102\u2010yl)urea <jats:bold>8<\/jats:bold>.<\/jats:p>","DOI":"10.1002\/ardp.19913240607","type":"journal-article","created":{"date-parts":[[2006,10,17]],"date-time":"2006-10-17T07:26:11Z","timestamp":1161069971000},"page":"355-357","source":"Crossref","is-referenced-by-count":5,"title":["Synthesis of New Benzimidazole Derivatives as Potential Antimicrobial Agents"],"prefix":"10.1002","volume":"324","author":[{"given":"El\u2010Sayed A. M.","family":"Badawey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed M. 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