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On the one hand, compounds with an arylamine group such as clozapine present a high reactivity in the horseradish peroxidase or myeloperoxidase systems and, on the other hand, fluperlapine, though known to induce agranulocytosis, and other debenzothiazepine and dibenzoxazepine derivatives appear insensitive to oxidation. Consequently, among tricyclic derivatives, the way of diaryloxa\u2010 and diarylthiazepine compounds could be an alternative for the development of safer drugs such as antipsychotics.<\/jats:p>","DOI":"10.1002\/ardp.19953280203","type":"journal-article","created":{"date-parts":[[2006,10,17]],"date-time":"2006-10-17T20:59:37Z","timestamp":1161118777000},"page":"109-112","source":"Crossref","is-referenced-by-count":13,"title":["Peroxidase\u2010catalysed oxidation of different dibenzazepine derivatives"],"prefix":"10.1002","volume":"328","author":[{"given":"Jean\u2010Francois","family":"Li\u00e9geois","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francoise","family":"Rogister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Delarge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00ebl","family":"Pincemail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,9,23]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"383","volume-title":"The Pharmacological Basis of Therapeutics","author":"Baldessarini R. 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