{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:50:21Z","timestamp":1790351421874,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","issue":"6-7","license":[{"start":{"date-parts":[[2003,8,25]],"date-time":"2003-08-25T00:00:00Z","timestamp":1061769600000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archiv der Pharmazie"],"published-print":{"date-parts":[[2003,8]]},"abstract":"Abstract<\/jats:title>A set of 40 derivatives of 3\u2010hydroxypicolinic acid and 2\u2010sulfanylbenzoic acid, isosteric to salicylanilides was synthesized. The compounds were evaluated for in vitro<\/jats:italic> activity against Mycobacterium tuberculosis<\/jats:italic>, Mycobacterium kansasii<\/jats:italic> and Mycobacterium avium<\/jats:italic>, Candida albicans<\/jats:italic>, Candida tropicalis<\/jats:italic>, Candida krusei<\/jats:italic>, Candida glabrata<\/jats:italic>, Trichosporon beigelii<\/jats:italic>, Aspergillus fumigatus<\/jats:italic>, Absidia corymbifera<\/jats:italic>, Trichophyton mentagrophytes<\/jats:italic> and Microsporum gypseum<\/jats:italic>. Structure\u2010activity relationships of antimycobacterial activity and antifungal activity against T. mentagrophytes<\/jats:italic> and M. gypseum<\/jats:italic> were analyzed by the Free\u2010Wilson method. An increase in antimycobacterial activity was observed only for the sulfanylbenzoic acid derivatives, especially those with the benzyl moiety. The antifungal activity was not significant.<\/jats:p>","DOI":"10.1002\/ardp.200300725","type":"journal-article","created":{"date-parts":[[2003,9,2]],"date-time":"2003-09-02T19:28:57Z","timestamp":1062530937000},"page":"322-335","source":"Crossref","is-referenced-by-count":28,"title":["Antimycobacterial and Antifungal Isosters of Salicylamides"],"prefix":"10.1002","volume":"336","author":[{"given":"Karel","family":"Waisser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Pe\u0161ina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Hol\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Pour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otakar","family":"Bure\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji\u0161\u00ed","family":"Kune\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u0161ra","family":"Klime\u0161ov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladim\u00edr","family":"Buchta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Kubanov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarmila","family":"Kaustov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,8,25]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1135\/cccc19970510"},{"key":"e_1_2_1_3_2","first-page":"335","volume":"54","author":"Schachtner J. E.","year":"1999","journal-title":"Pharmazie"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.200390004"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm9803572"},{"key":"e_1_2_1_6_2","unstructured":"K. Waisser J. Hladuvkov\u00e1 A. Hrab\u00e1lek V. Klime\u016fov\u00e1c L. Kubicov\u00e1 J. Kune\u016f M. Mach\u00e1cek K. Jr. Pal\u00e1t J. Sova J. Vin\u016fov\u00e1 V. Buchta P. J\u00edlek S. Odlerov\u00e1 in Postepy nauk farmaceutycznych (Eds. J. Pachecka J. J. Szewcz\u00fdnski) p. 34\u201346 Polskie towarzystwo farmaceuticzene Warszawa 1996."},{"key":"e_1_2_1_7_2","first-page":"69","author":"Waisser K.","year":"1998","journal-title":"Folia Pharm Univ. Carol."},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm00284a016"},{"key":"e_1_2_1_9_2","unstructured":"J. R. Geigy AG FR 13747111962[Chem. Abstr.1965 62 4011e]."},{"key":"e_1_2_1_10_2","unstructured":"R. Clauson\u2010Kaas US 32289501962[Chem. Abstr.1966 64 8152a]."},{"key":"e_1_2_1_11_2","first-page":"216","volume":"14","author":"Gialdi F.","year":"1959","journal-title":"Farmaco"},{"key":"e_1_2_1_12_2","first-page":"611","volume":"22","author":"Wagner G.","year":"1967","journal-title":"Pharmazie"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0040-4020(80)80182-7"}],"container-title":["Archiv der Pharmazie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fardp.200300725","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ardp.200300725","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T18:30:20Z","timestamp":1693420220000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ardp.200300725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8]]},"references-count":12,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["10.1002\/ardp.200300725"],"URL":"https:\/\/doi.org\/10.1002\/ardp.200300725","archive":["Portico"],"relation":{},"ISSN":["0365-6233","1521-4184"],"issn-type":[{"value":"0365-6233","type":"print"},{"value":"1521-4184","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,8]]}}}