{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:38:32Z","timestamp":1760783912683},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T00:00:00Z","timestamp":1422835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archiv der Pharmazie"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:label \/><jats:p>The antioxidant and radical scavenging activities of the synthesized compounds <jats:bold>3<\/jats:bold>, <jats:bold>5<\/jats:bold>, and <jats:bold>6<\/jats:bold> were determined by various <jats:italic>in vitro<\/jats:italic> assays such as 2,2\u2010azino\u2010bis(3\u2010ethylbenzthiazoline\u20106\u2010sulfonic acid radical (ABTS<jats:sup>\u00b7+<\/jats:sup>) scavenging, ferric ion (Fe<jats:sup>3+<\/jats:sup>) reducing power and ferrous ion (Fe<jats:sup>2+<\/jats:sup>) chelating activities. Moreover, these activities were compared to those of standard antioxidants such as butylated hydroxyanisole, butylated hydroxytoluene, and trolox. The results showed that the new compounds (<jats:bold>3<\/jats:bold>, <jats:bold>5<\/jats:bold>, and <jats:bold>6<\/jats:bold>) had potential antioxidant activity. Besides, inhibition of the two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I and II with some nitrobenzene compounds was investigated. Compounds <jats:bold>1\u20136<\/jats:bold> showed <jats:italic>K<\/jats:italic><jats:sub>i<\/jats:sub> values in the range of 4.88\u2013193.4\u2009\u00b5M and 5.295\u201354.75\u2009\u00b5M for hCA I and hCA II, respectively.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ardp.201400330","type":"journal-article","created":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T20:23:08Z","timestamp":1422908588000},"page":"214-220","source":"Crossref","is-referenced-by-count":4,"title":["Synthesis and Determination of Some Biological Activities of Novel 2,4\u2010Dinitrophenyl Derivatives"],"prefix":"10.1002","volume":"348","author":[{"given":"Sevim B.","family":"\u00d6zt\u00fcrk Sarikaya","sequence":"first","affiliation":[{"name":"Engineering and Natural Sciences Faculty Food Engineering Department Gumushane University Gumushane Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Af\u015fin A.","family":"Kaya","sequence":"additional","affiliation":[{"name":"School of Health Gumushane University Gumushane Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elif \u00c7elenk","family":"Kaya","sequence":"additional","affiliation":[{"name":"School of Health Gumushane University Gumushane Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"\u015eent\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Chemistry Art and Science Faculty Agri Ibrahim Cecen University Agri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2004.04.017"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1995-7645(10)60216-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2010.11.014"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2005.11.004"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-011-0774-2"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00436-002-0754-9","volume":"90","author":"Raether W.","year":"2003","journal-title":"Parasitol. 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