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Two iodide salts were synthesized by the anion exchange reaction of the corresponding <jats:italic>p<\/jats:italic>\u2010toluenesulfonate salt and NaI. All compounds were characterized by <jats:sup>1<\/jats:sup>H NMR, <jats:sup>13<\/jats:sup>C NMR, IR, LC\u2010MS spectroscopic methods, and elemental analyses. The crystal structure of 1\u2010methoxyethyl\u20101<jats:italic>H<\/jats:italic>\u2010benzimidazolium <jats:italic>p<\/jats:italic>\u2010toluenesulfonate <jats:bold>2d<\/jats:bold> showed that cation and anion are interconnected by N\u2212H\u00b7\u00b7\u00b7O and C\u2212H\u00b7\u00b7\u00b7O hydrogen bonds. All compounds were examined as inhibitor of human carbonic anhydrase (hCA) I and II, and all of them inhibited hCA I and hCA II. Kinetic investigation results revealed that these compounds inhibit hCA I and hCA II in a non\u2010competitive manner. The iodide salts had higher inhibitory activity than their corresponding <jats:italic>p<\/jats:italic>\u2010toluenesulfonate salts.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ardp.201800325","type":"journal-article","created":{"date-parts":[[2019,1,8]],"date-time":"2019-01-08T19:51:55Z","timestamp":1546977115000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Microwave\u2010assisted synthesis of 1\u2010substituted\u20101<i>H<\/i>\u2010benzimidazolium salts: Non\u2010competitive inhibition of human carbonic anhydrase I and II"],"prefix":"10.1002","volume":"352","author":[{"given":"\u00d6zg\u00fcl","family":"Karl\u0131k","sequence":"first","affiliation":[{"name":"Faculty of Arts and Science, Department of Chemistry \u0130n\u00f6n\u00fc University Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahit","family":"Gen\u00e7er","sequence":"additional","affiliation":[{"name":"Faculty of Arts 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