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The identification and quantification of the extract compounds were done using ultra\u2010high\u2010performance liquid chromatography, with a diode array detector coupled with triple\u2010quadrupole mass spectrometer and gas chromatography\u2013mass spectrometry techniques. Thirty\u2010one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5\u2010<jats:italic>O<\/jats:italic>\u2010caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram\u2010positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against <jats:italic>Enterococcus faecalis<\/jats:italic> ATCC 19433 and <jats:italic>Listeria monocytogenes<\/jats:italic> ATCC 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties.<\/jats:p>","DOI":"10.1002\/ardp.202000195","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T19:24:43Z","timestamp":1602617083000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Chemical composition and antimicrobial activity of Osage orange (<i>Maclura pomifera<\/i>) leaf extracts"],"prefix":"10.1002","volume":"354","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4113-9247","authenticated-orcid":false,"given":"Sne\u017eana","family":"Filip","sequence":"first","affiliation":[{"name":"Technical Faculty \u201cMihajlo Pupin\u201d Zrenjanin University of Novi Sad  Zrenjanin Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sa\u0161a","family":"\u0110urovi\u0107","sequence":"additional","affiliation":[{"name":"Institute of General and Physical Chemistry  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stevan","family":"Blagojevi\u0107","sequence":"additional","affiliation":[{"name":"Institute of General and Physical Chemistry  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Tomi\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Technology University of Novi Sad  Novi Sad Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Ranitovi\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Technology University of Novi Sad  Novi Sad Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uro\u0161","family":"Ga\u0161i\u0107","sequence":"additional","affiliation":[{"name":"Department of Plant Physiology, National Institute of Republic of Serbia University of Belgrade  Belgrade Serbia"},{"name":"Faculty of Chemistry University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u017divoslav","family":"Te\u0161i\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Chemistry University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoran","family":"Zekovi\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Technology University of Novi Sad  Novi Sad Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/np9904509"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/162750"},{"key":"e_1_2_8_4_1","first-page":"1","volume":"18","author":"Gorniak I.","year":"2018","journal-title":"Phytochem. 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