{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T02:23:50Z","timestamp":1774405430327,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T00:00:00Z","timestamp":1699401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Archiv der Pharmazie"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study introduces a new method for analyzing rifampicin, moxifloxacin, and metronidazole using a green micellar High Performance Liquid Chromatography\u2010Ultraviolet method in bulk drugs, different commercial formulations, and spiked human plasma. The combined therapy of these three broad\u2010spectrum antibiotics is used to cure refractory hidradenitis suppurativa (HS), an inflammatory condition affecting the skin. The sustainable separation was attained on a reversed\u2010phase C18 Kinetex\u00ae column maintained at ambient temperature in less than 5\u2009min. The mobile phase comprises 0.1\u2009M sodium dodecyl sulfate (SDS) in water, pH 3.5, adjusted using <jats:italic>o\u2010<\/jats:italic>phosphoric acid, and 10% <jats:italic>n<\/jats:italic>\u2010butanol. The flow rate was 1\u2009mL\/min, with 10\u2009\u03bcL injection volume and UV detection at 230\u2009nm. The impact of three key significant variables, SDS concentration, <jats:italic>n<\/jats:italic>\u2010butanol percentage, and the mobile phase pH, on suitability parameters was studied. ICH and FDA guidelines were committed to when validating the technique. The results showed linear calibration graphs with high precision and accuracy, in both pure and spiked plasma. The method is efficient, easy to use, and has a high sample throughput, making it suitable for routine analysis in the quality control department and therapeutic monitoring. It is also evaluated as a green\u2010and\u2010white substitute for traditional reported methods.<\/jats:p>","DOI":"10.1002\/ardp.202300509","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T20:40:01Z","timestamp":1699476001000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Eco\u2010friendly micellar HPLC approach for simultaneous estimation of combination therapy for hidradenitis suppurativa: Applications to spiked human plasma and different dosage forms"],"prefix":"10.1002","volume":"357","author":[{"given":"Asmaa M.","family":"Taha","sequence":"first","affiliation":[{"name":"Analytical Chemistry Department, Faculty of Pharmacy Zagazig University Zagazig Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wafaa S.","family":"Hassan","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Department, Faculty of Pharmacy Zagazig University Zagazig Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3120-5909","authenticated-orcid":false,"given":"Manal S.","family":"Elmasry","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Department, Faculty of Pharmacy Zagazig University Zagazig Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rania A.","family":"Sayed","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Department, Faculty of Pharmacy Zagazig University Zagazig Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-0149-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12793"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000321716"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4001"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.198510093"},{"key":"e_1_2_6_7_1","volume-title":"Martindale, The Complete Drug Reference","author":"Sweetman S. C.","year":"2007"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e31819476fa"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2020.113137"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2022.123496"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2RA01631A"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2016.07.054"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-32494-8"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781482273816"},{"key":"e_1_2_6_15_1","first-page":"877","volume":"13","author":"El\u2010Shaheny R. N.","year":"2015","journal-title":"Open Chem. J"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(99)00430-2"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2008.05.003"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2016.04.026"},{"key":"e_1_2_6_19_1","volume-title":"Validation of Analytical Procedures: Text and Methodology Q2 (R1)","author":"ICH\u2010Guidelines","year":"2005"},{"key":"e_1_2_6_20_1","unstructured":"Food and Drug Administration Guidance for Industry: Bioanalytical Method Validation.https:\/\/www.fda.gov\/files\/drugs\/published\/Bioanalytical-Method-Validation-Guidance-for-Industry.pdf(accessed: September 2023)."},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007691-198303000-00004"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-59681-0_22"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.6.6.691"},{"key":"e_1_2_6_24_1","unstructured":"USP\u2013NF. The United States Pharmacopeia 41st edition The National Formulary 36th edition. United States Pharmacopeial Convention Inc. Asian edition Washington DC2018."},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1039\/c3ay41221k"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2019.04.074"},{"key":"e_1_2_6_27_1","first-page":"241","volume":"4","author":"Ghante M. R.","year":"2012","journal-title":"Int. J. Pharm. Pharm. Sci"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.0c01887"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2018.01.013"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2023.117196"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2012.03.013"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2021.116223"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-24761-x"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-9140(98)00111-8"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2006.11.023"},{"key":"e_1_2_6_36_1","first-page":"106","volume":"3","author":"Das J.","year":"2014","journal-title":"J. PharmaSciTech"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-820007-0.00032-5"}],"container-title":["Archiv der Pharmazie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ardp.202300509","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T04:48:16Z","timestamp":1706935696000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ardp.202300509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,8]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1002\/ardp.202300509"],"URL":"https:\/\/doi.org\/10.1002\/ardp.202300509","archive":["Portico"],"relation":{},"ISSN":["0365-6233","1521-4184"],"issn-type":[{"value":"0365-6233","type":"print"},{"value":"1521-4184","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,8]]},"assertion":[{"value":"2023-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2300509"}}