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In the biologic augmentation (BA) group, the LHBT was extracted, pressed, and augmented on the repair site. Histological evaluation was performed at 3 and 6\u2009weeks to measure the thickness of the repaired tendon, number of chondrocytes and non\u2010chondrocytes, percentage of aligned chondrocytes, areas of fibrocartilage and collagen fiber, and COL1\/COL3 ratio. Genetic expression of collagen types 1 and 3 (COL1 and COL3, respectively); matrix metalloproteinases\u20101, 3, and 13; and transforming growth factor beta were measured at 3 and 6\u2009weeks. Mechanical testing was performed at 3 and 6\u2009weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Tendon thickness (3.72\u2009mm vs 2.83\u2009mm;\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .01), number of chondrocytes (73.8 vs 39.7;\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .01), fibrocartilage area (0.35 vs 0.22\u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      ;\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .03), and collagen fiber area (0.20 vs 0.11\u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      ;\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .03) at 6\u2009weeks were significantly higher in the BA group than in the control group. COL1\/COL3 ratio at 3 and 6\u2009weeks was significantly higher in the BA group than in the control group (3\u2009weeks, 1.01 vs 0.51;\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .01 and 6\u2009weeks, 0.68 vs 0.27;\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .04). COL3 expression at 6\u2009weeks was significantly lower in the BA group (\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .02). Matrix metalloproteinase\u20101 expression at 3\u2009weeks was significantly higher in the BA group (\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .005). The ultimate load to failure at 6\u2009weeks was significantly higher in the BA group (51.5\u2009N vs 31.5\u2009N;\n                      <jats:italic>P\u2009=\u2009<\/jats:italic>\n                      .03).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Biological augmentation using pressed autologous LHBT promoted tendon\u2010to\u2010bone healing and enhanced mechanical strength.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>Augmentation with pressed LHBT may improve the biology and mechanical strength of rotator cuff repair.<\/jats:p>\n                  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